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The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.

Finasteride treatment in rats changed the expression of genes related to psychiatric and neurological functions, and these changes persisted after stopping the drug.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Skin health and diseases are closely linked to metabolic processes.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Innovative methods are reducing animal testing and improving biomedical research.

Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.

Electro-acupuncture may help treat PCOS in rats by changing brain DNA methylation.

Traditional Chinese medicinal foods may help manage long-term post-COVID symptoms.

The document describes skin diseases affecting the outer ear in dogs and cats, their spread to other body parts, and treatment options.

Finasteride improves heart function and repairs damage after heart attack in mice.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.

The consensus provided guidelines for treating the Female Athlete Triad and a system to decide when athletes can return to sports.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

Injecting minced fat into the facial artery can cause severe eye problems and death, more so than other fat types, and larger amounts increase these risks.

The research found that anovulatory young women have higher androgen and hormone levels than those who ovulate, suggesting immature hormonal regulation rather than a specific condition.

Premature hair graying may be a sign of increased risk for heart disease, indicating biological age is more important than actual age.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

Innovative biomaterials show promise in healing chronic diabetic foot ulcers.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.

Taking triterpenoids from Ganoderma lucidum over a long time can help slow down brain aging and improve overall health in mice.

Bioprinting could improve wound healing but needs more development to match real skin.