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Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

Basal cell carcinomas have much higher levels of Vitamin D3 receptors compared to healthy skin.

Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.

Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

CD4+ skin cells may be precursors to basal cell carcinoma.

Treatments improved hair surface and scale structure but didn't increase certain bonds in the hair cortex.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

A small group of slow-growing cells causes basal cell carcinoma to return after treatment.

The extracellular matrix affects where tumors can start in the body.

External factors can cause skin cancer cells that usually don't spread to grow and form tumors in mice.

Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.

Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.

In 2011, hair restoration was a specialized field in plastic surgery, using techniques like "Ultrarefined follicular unit hair transplantation" to minimize scarring and promote hair growth, with future treatments like stem cell therapy and hair cloning still being tested.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Different types of skin cells play specific roles in development, healing, and cancer.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

New markers and pathways have been found in skin tumors, helping better understand and diagnose them.

Certain spices may help prevent and treat skin cancer, but more human trials are needed.

Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.