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![Clinical Course of the First Japanese Family with Marie Unna Hereditary Hypotrichosis: A Follow-Up Report](/images/research/0b931ebd-cd8d-4a59-a08e-03e896fb21cc/small/17932.jpg)
research Clinical Course of the First Japanese Family with Marie Unna Hereditary Hypotrichosis: A Follow-Up Report
The first Japanese family with Marie Unna hereditary hypotrichosis showed hair condition improvement in a child and highlighted the risk of misdiagnosis.
![Skin Disorders in Athletes: Professional and Recreational Sports](/images/research/c5db3474-b554-44ae-b4a6-dcb1466317f8/small/18043.jpg)
research Skin Disorders in Athletes: Professional and Recreational Sports
Athletes need effective management of skin disorders for their performance and well-being.
![Neuroimaging of Sleep and Depression](/images/research/c516e2c2-4d79-4e55-b4e2-e796876db09b/small/18074.jpg)
research Neuroimaging of Sleep and Depression
Sleep problems and skin issues affect each other; poor sleep can worsen skin conditions, and some skin treatments can improve or harm sleep quality.
![Skin Disorders](/images/research/687023aa-c2b6-4c54-88cc-0847d977fe82/small/26062.jpg)
research Skin Disorders
Older adults often have skin problems due to aging, and treating these conditions requires attention to both physical and mental health.
![Principles of Therapy of Skin Diseases](/images/research/e8884924-c739-4eb2-86fc-a2ef40316b00/small/14624.jpg)
research Principles of Therapy of Skin Diseases
Use the least toxic, most specific treatments for skin diseases, considering side effects and individual patient needs.
![Dermatological History and Examination](/images/research/f61c808c-b1d8-4c8c-8775-48335bc74a94/small/15308.jpg)
research Dermatological History and Examination
A thorough history and examination are crucial for diagnosing skin diseases, which affect up to a third of people. This includes details about skin lesions, medication, general health, lifestyle, family, and contacts, as well as examining the rash, hair, nails, and mucous membranes. Changes in hair and nails can also indicate other medical and skin disorders.
![In Vivo Reflectance Confocal Microscopy: Usefulness for Diagnosing Hair Diseases](/images/research/c421f117-7f95-48bd-999a-c2964db1559c/small/15089.jpg)
research In Vivo Reflectance Confocal Microscopy: Usefulness for Diagnosing Hair Diseases
In vivo reflectance confocal microscopy is useful for evaluating hair shaft diseases but needs improvement for deeper hair follicle issues.
research Topical Fluocinolone Acetonide Acetate Ointment in Autosomal Dominant Congenital Hypotrichosis
A hair growth ointment improved hair length in a family with a genetic hair growth condition.
![The Color of Skin: White Diseases of the Skin, Nails, and Mucosa](/images/research/c691442a-66b8-4814-ae6d-f7cdd3cdc37a/small/13415.jpg)
research The Color of Skin: White Diseases of the Skin, Nails, and Mucosa
The document concludes that while white skin, nail, and mucosa diseases increase skin cancer risk, they are generally harmless, especially compared to darker pigmentation conditions.
![Validity and Advantages of Three-Dimensional High-Frequency Ultrasound in Dermatological Evaluation](/images/research/3860557b-8771-4f79-8ed8-0abd2ef6043b/small/41217.jpg)
research Validity and Advantages of Three-Dimensional High-Frequency Ultrasound in Dermatological Evaluation
3D high-frequency ultrasound can help diagnose skin and hair conditions without invasive biopsies.
research 25-Year-Old Woman With New-Onset Seizures
A woman's new seizures were caused by a brain tumor likely linked to her past cancer treatment, and choosing safe seizure medications is important for women who can have children.
research Epidermal Growth Factor Receptor Inhibitors: A Review of Cutaneous Adverse Events and Management
Skin side effects from cancer drugs targeting EGFR can affect treatment adherence but can be managed with antibiotics like tetracycline.
research Pili Torti: A Feature of Numerous Congenital and Acquired Conditions
Pili torti is a rare condition where hair is twisted and breaks easily, often linked to genetic disorders or other health issues.
![Skin Cancers and Their Risk Factors in Older Persons: A Population-Based Study](/images/research/3a938687-3869-44c2-8f63-61a1f16179d1/small/15773.jpg)
research Skin Cancers and Their Risk Factors in Older Persons: A Population-Based Study
Older men and those with a history of skin cancer have a higher risk of getting skin cancer again.
![A Review of the Most Common Dermatologic Conditions and Their Debilitating Psychosocial Impacts](/images/research/abb6c561-163a-441c-8d21-a69af952fb25/small/20893.jpg)
research A Review of the Most Common Dermatologic Conditions and Their Debilitating Psychosocial Impacts
Common skin conditions can greatly affect a person's mental health and social life.
research The Spectrum of Cutaneous Manifestations in Lupus Erythematosus: A Comprehensive Review
Recognizing specific skin features helps diagnose and manage lupus erythematosus effectively.
![The Glypican-1/HGF/C-Met and Glypican-1/VEGF/VEGFR2 Ternary Complexes Regulate Hair Follicle Angiogenesis](/images/research/de0851b0-27b5-4daa-a646-819e92ba867c/small/35185.jpg)
research The Glypican-1/HGF/C-Met and Glypican-1/VEGF/VEGFR2 Ternary Complexes Regulate Hair Follicle Angiogenesis
Glypican-1 is important for blood vessel growth in hair follicles and could help treat hair loss.
research Cytochrome P450: A Target for Drug Development for Skin Diseases
Modulating Cytochrome P450 activity could help develop new skin disease treatments.
![Docetaxel and Oxaliplatin in the Second-Line Treatment of Platinum-Sensitive Recurrent Ovarian Cancer: A Phase II Study](/images/research/76726140-f014-44a7-a69b-6bf4d140177b/small/25817.jpg)
research Docetaxel and Oxaliplatin in the Second-Line Treatment of Platinum-Sensitive Recurrent Ovarian Cancer: A Phase II Study
Docetaxel and oxaliplatin are effective and have manageable side effects for recurrent platinum-sensitive ovarian cancer.
![Abstracts](/images/research/06d42272-f5c5-4930-8e54-364960aa0fc0/small/17395.jpg)
research Abstracts
New treatments and diagnostic methods for various animal skin conditions showed promising results.
![MicroRNA-214 Controls Skin and Hair Follicle Development by Modulating the Activity of the Wnt Pathway](/images/research/872e88ad-c146-4882-b90a-c091c18228f0/small/18756.jpg)
research MicroRNA-214 Controls Skin and Hair Follicle Development by Modulating the Activity of the Wnt Pathway
MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
![Aging in Hair Follicle Stem Cells and Niche Microenvironment](/images/research/c250aa11-255b-4a9a-9356-d63fb8b4e124/small/18210.jpg)
research Aging in Hair Follicle Stem Cells and Niche Microenvironment
Aging in hair follicle stem cells leads to hair graying, thinning, and loss.
![Polygonum Multiflorum Extract Supports Hair Growth by Elongating Anagen Phase and Abrogating the Effect of Androgen in Cultured Human Dermal Papilla Cells](/images/research/7f6c1c7d-5020-437b-a6f1-8e48f57790ff/small/13303.jpg)
research Polygonum Multiflorum Extract Supports Hair Growth by Elongating Anagen Phase and Abrogating the Effect of Androgen in Cultured Human Dermal Papilla Cells
Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.
research DNMT1-Mediated Methylation Inhibits MicroRNA-214-3p and Promotes Hair Follicle Stem Cell Differentiation Into Adipogenic Lineages
DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.
research Wnt/β-Catenin Signaling Stabilizes Hemidesmosomes in Keratinocytes
Wnt/β-catenin signaling is important for keeping skin cell attachment structures stable.
![The Role of P-Cadherin in Skin Biology and Pathology: Lessons from the Hair Follicle](/images/research/431511b3-197c-47d0-8aef-9f8fd8f90119/small/29180.jpg)
research The Role of P-Cadherin in Skin Biology and Pathology: Lessons from the Hair Follicle
P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.
![EGFR Inhibitors and Cutaneous Complications: A Practical Approach to Management](/images/research/3ca8c1b3-4812-4d19-924c-c6b684f6e831/small/27708.jpg)
research EGFR Inhibitors and Cutaneous Complications: A Practical Approach to Management
The document provides advice on how to recognize and treat skin-related side effects of cancer drugs known as EGFR inhibitors.
![Semiology of Skin Toxicity Associated with Epidermal Growth Factor Receptor Inhibitors](/images/research/ae33eed6-7eb3-4924-a132-553d2ea87c31/small/14627.jpg)
research Semiology of Skin Toxicity Associated with Epidermal Growth Factor Receptor Inhibitors
Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.
![Regulated Proenkephalin Expression in Human Skin and Cultured Skin Cells](/images/research/b19c22e8-a06f-4002-9339-1c7285043c07/small/34945.jpg)
research Regulated Proenkephalin Expression in Human Skin and Cultured Skin Cells
Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.