January 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study identified non-structural proteins in preschool children's scalp hair that suggest potential biomarkers for brain development, immune function, and stress response with heritability and age-related differences.
January 2019 in “Institutional Repositories DataBase (IRDB)” This study developed in vitro methods to regenerate hair follicles and erector muscles by mimicking their native structures and mechanical conditions, reconstructing hair follicle-like structures and forming muscle-like tissues.
55 citations
,
February 2014 in “Journal of Structural Biology” This study observed that human hair macrofibrils predominantly exhibit a double-twist architecture with varying inter-macrofibril angles, advancing insights into their structural organization and mechanical implications.
12 citations
,
January 2015 in “Skin appendage disorders” This article illustrates that dermoscopy can quickly diagnose hair breakage due to intrinsic and chemical factors in patients of African descent, although published findings are limited.
May 2026 in “Materials & Design” This study developed a hair-on-a-chip model that supports the maturation of hair-follicle-like tissue under long-term culture conditions, suggesting its promise for studying hair regeneration and testing scalp-targeted therapies.
August 2024 in “Indian Dermatology Online Journal” In this retrospective study, researchers described the dermoscopic features of dermatitis cruris pustulosa et atrophicans in 30 patients, finding that follicular-based pustules and other specific features were predominant, with male patients being more affected and primarily involving the lower extremities.
30 citations
,
January 2013 in “International Journal of Trichology” This study found that in Jordanian children, tinea capitis, alopecia areata, and telogen effluvium were the most common causes of hair loss, with nutritional deficiencies such as iron and zinc deficiency also noted as significant factors.
December 2022 in “Aesthetic Cosmetology and Medicine” This review discusses various methods to treat androgenetic alopecia in men and reports that certain treatments can significantly alleviate its severity, without presenting new clinical results.
30 citations
,
April 2017 in “Journal of structural biology” This study suggests that human keratin fiber matrix has a well-defined nano-scale grainy structure rather than being amorphous, with grain size influenced by chemical treatments, temperature, humidity, and follicle-level factors.
This article discusses the structure and protective function of pangolin scales, emphasizing their composition of α-keratins and β-keratins, and highlights evolutionary keratin diversification in tetrapods; it reports no new empirical findings.
14 citations
,
September 2001 in “Dermatologic Surgery” This review derived guidelines for scalp surgery suggesting improved outcomes when avoiding neurovascular structures, preserving tissue integrity, and maintaining hair direction, but it reports no new clinical results.
September 2019 in “Journal of Investigative Dermatology” This study found that co-culturing dermal papilla cells in a 3D structure with adipose-derived stem cells may enhance the expression of hair inductivity markers compared to 2D cultures.
51 citations
,
January 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified a novel keratin-associated protein, KAP24.1, which is specifically expressed in the human scalp and located in the hair cuticle.
14 citations
,
December 2020 in “Journal of Investigative Dermatology” This study observed that aging leads to significant structural and biological changes in the scalp's hair follicle environment in women, which may affect hair growth.
This study analyzed scalp hair proteins from healthy children and their mothers, finding that non-structural proteins could serve as promising biomarkers for understanding long-term developmental changes and health status linked to early childhood experiences.
October 2025 in “International Journal of Molecular Sciences” This study identified changes in immune activation, ferroptosis, and structural genes in alopecia areata subtypes, suggesting molecular markers that might help understand disease variability and guide future treatments.
158 citations
,
January 2009 in “The International Journal of Developmental Biology” This perspective highlights the potential of reptile integument as an experimental model to understand the evolution of amniote skin structures, but reports no new research findings.
2 citations
,
December 2025 in “Cosmetics” This review reports on the effects of aging on hair characteristics such as pigmentation, growth, and structural properties across genders and ethnicities, highlighting the importance of scalp health and suggesting cosmetic solutions to improve the appearance of aged hair.
1 citations
,
March 2017 in “Roczniki Naukowe Polskiego Towarzystwa Zootechnicznego” In this study, researchers observed that underhairs in domestic cats were the thinnest and shortest with regular scales, while guard hairs were the longest and thickest, having irregular scales.
April 2019 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study identified three new genetic loci associated with PCOS and found a similar genetic structure across different diagnostic criteria, suggesting a genetic basis for shared metabolic traits and potential causal links to other conditions.
1 citations
,
January 2018 in “Journal of Society of Cosmetic Chemists of Japan” In this study involving Japanese women, researchers found that higher scalp oil levels were linked to weaker hair structure and increased scalp inflammation, suggesting that plant-derived compounds might mitigate these effects by reducing inflammation at the genetic level.
August 2023 in “ACS applied materials & interfaces” In this study, researchers developed an innovative wound healing patch combining electrical and chemical components, which effectively guided recovery in animal scald models by promoting collagen deposition and the regeneration of skin structures.
January 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study found that ageing in women leads to significant structural and biological changes in the scalp hair follicle environment, which may affect hair growth.
9 citations
,
March 2014 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” This study developed a novel multi-scale image descriptor using dictionaries for classifying histological images, achieving average recall and precision measures of 0.81 and 0.86 in identifying specific skin structures and pathologies.
January 1991 in “Journal of Society of Cosmetic Chemists of Japan” In this study, researchers found that specific enzyme activities in young females' hair follicles were correlated with changes in hair shaft structure and properties, and permanent waving was associated with chemical changes that suggest hair damage.
2 citations
,
September 2002 in “Dermatologic Surgery” This study describes how arrector pili muscles form a single muscular structure shared by all hair follicles within a follicular unit at the isthmus level in scalp skin.
2 citations
,
December 2004 in “Medicine” This review discusses various causes of hair loss, emphasizing the importance of a structured diagnostic approach, and reports no new clinical findings.
November 2025 in “Journal of Investigative Dermatology” NUL-5 may boost hair growth by improving hair follicle health and structure.
5 citations
,
August 2016 in “International Journal of Cosmetic Science” In this in-vitro study, researchers found that shampoo-induced coacervates structurally resemble cationic polymers and contain anionic surfactants that may stimulate the scalp upon exposure to water.
13 citations
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April 2022 in “BMC Genomics” This study found that dandruff-afflicted individuals had a less integrated microbial network on the scalp and hair surface compared to healthy individuals, with more positive interactions and unstable connections.