April 2026 in “Pharmaceutics” This review highlights cellulose-based materials' potential in skin disease treatments, emphasizing their smart, responsive design for various conditions, with insights into their roles in wound healing, infection prevention, and wearable monitoring.
February 2026 in “Biomaterials” BOOST is a promising, easy-to-use treatment for diabetic foot ulcers that improves healing by reducing inflammation and promoting blood vessel growth.
January 2026 in “Materialia” In this study, porcine collagen acellular dermal matrix scaffolds combined with mice platelet-rich plasma were associated with increased hair density and follicle regeneration in mice with alopecia, suggesting a potential therapeutic approach.
December 2025 in “Materials Technology” In this laboratory study, researchers developed a genipin-stabilized asymmetric PLA/gelatin scaffold that mimics skin architecture, supports fibroblast proliferation, and closes scratches effectively, suggesting its potential for epidermal-dermal regeneration and applications in sensing or drug delivery.
September 2023 in “Nature Communications” In this animal study, the researchers found that biodegradable extracellular matrix scaffolds accelerated wound healing and enhanced hair follicle neogenesis in mice, suggesting a role for immune systems in tissue regeneration.
August 2023 in “European Journal of Plastic Surgery” This study found that although three-dimensional bioprinting in plastic and reconstructive surgery is rapidly advancing, complete tissue systems have not yet been successfully printed due to ongoing challenges.
November 2022 in “IntechOpen eBooks” This review discusses nanoparticle-based wound-healing materials, detailing their benefits, limitations, and recent advancements, and emphasizes the need for further understanding to enhance therapeutic outcomes.
This study demonstrated that cryogelation of human hair keratin allows the development of 3D scaffolds with tunable properties, supporting cell adhesion and proliferation for potential biomedical applications.
June 2018 in “Journal of Acupuncture and Meridian Studies” This study reports that an electrochemical biosensor using a gold and palladium-modified electrode effectively detects levodopa and uric acid in various samples, offering improved performance over previous electrodes.
January 2006 in “Chinese Journal of Aesthetic Medicine” This study found that a new-type artificial xenogenic derma exhibited better biocompatibility and dermal tissue regeneration ability compared to cross-linked acellular dermal matrix in a mouse model.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study suggests that 3D bioprinting may become a practical solution for tissue regeneration and complex wound care, demonstrating improved outcomes over traditional methods in various applications.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study demonstrates that 3D bioprinting is advancing toward practical use in reconstructive medicine, with promising results in personalized skin grafts, hair regeneration, and burn care, despite existing technical and ethical challenges.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review reports that nanoparticles, especially those optimized to 300-400nm, may enhance follicular drug delivery compared to conventional formulations, offering targeted therapy for conditions like androgenic alopecia, acne, and psoriasis.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights advancements in transfollicular drug delivery, noting that nanoparticles optimized to 300-400nm improve drug penetration into hair follicles better than conventional formulations, and that novel stimulus-responsive systems offer enhanced targeted delivery for conditions like androgenic alopecia and acne.
June 2023 in “Juan Cuevas eBooks” This volume is part of a series intended to educate plastic and reconstructive surgeons, residents, and other medical professionals, but the abstract does not report specific research findings.
April 2023 in “ACS Biomaterials Science & Engineering” This review highlights the importance of using 3D scaffolds in vitro to support hair follicle regeneration, emphasizing how these structures help maintain cell function and mimic the natural environment, which is crucial for developing hair follicle organoids for transplantation.
294 citations
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January 2016 in “Stem Cells International” This review discusses the characteristics, biomaterials, and tissue engineering methods for adipose-derived stem cells in a 3D environment, highlighting their potential in regenerative medicine without presenting new clinical results.
115 citations
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August 2014 in “Jo'jig gonghag gwa jaesaeng uihag/Tissue engineering and regenerative medicine” Human hair keratin can be used in many medical applications.
102 citations
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April 2014 in “PloS one” In this study, Wharton’s Jelly Mesenchymal Stem Cells, cultured with human platelet lysate, showed enhanced wound-healing capabilities and multilineage differentiation potential, distinguishing them from bone marrow-derived stem cells and presenting exciting prospects for regenerative medicine.
55 citations
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April 2018 in “Advanced Healthcare Materials” This review discusses recent advances in scarless wound healing, focusing on strategies to create pro-regenerative scaffolds for repairing damaged skin, and reports no new clinical results.
50 citations
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February 2022 in “Nanomaterials” This review discusses the mechanisms involved in wound healing and explores the potential of nanomaterials as a promising approach to managing chronic wounds, but reports no new clinical findings.
23 citations
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June 2015 in “Journal of Tissue Engineering and Regenerative Medicine” This study demonstrated that a 3D air–liquid culture system using Wnt-CM-treated cells can induce hair regeneration in nude mice and may facilitate large-scale preparation for hair loss treatment.
19 citations
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March 2021 in “Applied Materials Today” This study found that silk fibroin gel induced more pro-regenerative macrophages and hair follicle stem cells, leading to almost scarless skin regeneration compared to alginate gel.
14 citations
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April 2017 in “Scientific Reports” This study demonstrated that using a perfusion culture bioreactor and 3D spheroid culture can enhance corneal endothelial cell expansion and support the construction of tissue-engineered corneal endothelial layers in vitro.
13 citations
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March 2024 in “Cell Transplantation” This review highlights the need for improved methods in cosmetic safety assessment, emphasizing the potential of engineered skin tissue for more effective detection and toxicological evaluation of cosmetic products, compared to traditional methods.
7 citations
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May 2023 in “Macromolecular Bioscience” This review discusses recent advancements in using macromolecules for hair loss treatment, highlighting microneedle and nanoparticle delivery systems, tissue-engineered scaffolds for hair follicle regeneration, and artificial skin platforms as drug screening methods.
4 citations
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January 2017 in “PubMed” This study found that adding epidermal growth factor to mesenchymal stem cells enhanced wound healing and hair follicle regeneration in rats compared to stem cells alone.
4 citations
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June 2007 in “PubMed” This study found that using engineered skin with PGA-collagen scaffolds, combined with hair follicle stem cells and other cell types, effectively repaired full-thickness skin defects in nude mice.
September 2026 in “Mendeley Data” This study found that the polyurethane-cellulose acetate scaffold containing plasma rich in growth factors enhanced gene expression linked to wound healing compared to controls.
September 2026 in “Mendeley Data” This study found that a polyurethane-cellulose acetate scaffold with plasma rich in growth factors may enhance gene expression related to wound healing in an experimental setting.