32 citations
,
December 2017 in “Stem Cells Translational Medicine” This review discusses how studying regenerative biology in certain mammalian models could enhance our understanding of complex tissue regeneration, but it reports no new clinical findings.
31 citations
,
August 2019 in “Regenerative Medicine” This study found that the human placenta extracellular matrix hydrogel restored the hair-inductive capacity of high-passaged dermal papilla cells, enabling them to regenerate new hair follicles when co-grafted with mouse epidermal cells.
30 citations
,
May 2019 in “Medicinal Research Reviews” This review discusses molecular and cellular strategies to improve muscle and skin regeneration and reduce scarring after cleft lip repair, offering potential benefits for function and aesthetics.
29 citations
,
May 2025 in “Polymers” This study systematically examines how smart biomaterials used with DLP technology can enhance bioprinting in tissue engineering and regenerative medicine, while also identifying current challenges and future research needs.
27 citations
,
May 2011 in “Current Opinion in Ophthalmology” This study reports that a new transplantation technique using tissue-engineered stem cells successfully reconstructed corneal epithelium in an animal model of severe ocular surface disease.
26 citations
,
August 2024 in “Frontiers in Bioengineering and Biotechnology” This review aims to systematically evaluate the various types of antimicrobial wound dressings and current research on antimicrobial agents, providing insights for innovative treatments of infected wounds, due to the lack of comprehensive studies on their efficacy in promoting wound healing.
24 citations
,
November 2023 in “Regenerative Biomaterials” In this review, the authors summarized the potential therapeutic effects of metal ions in treating cardiovascular diseases, highlighting their roles in protecting cells, inducing angiogenesis, and adjusting ion channel functions, as well as discussing delivery strategies involving biomaterials.
24 citations
,
August 2023 in “International Journal of Molecular Sciences” This review discusses the use of platelet-rich fibrin (PRF) in musculoskeletal, oral, and maxillofacial surgeries and dermatology, but reports no new clinical results; further trials are needed.
23 citations
,
May 2019 in “Stem cell research & therapy” This study found that combining a human acellular amniotic membrane with iPSC-derived epithelial stem cells effectively repaired skin defects and promoted hair follicle formation in nude mice.
17 citations
,
August 2024 in “Discover Nano” This review summarizes that polyesters hold promise for vascular tissue engineering due to their mechanical properties and biodegradability, but optimizing their use in repairing damaged blood vessels remains challenging due to the complexity of vascular tissues.
17 citations
,
October 2023 in “Polymers” This review highlights advancements in electrospun nanofibers, focusing on their potential applications in biomedical technologies, chemical and biological sensing, and energy harvesting within IoT devices.
15 citations
,
November 2024 in “Materials” This review discusses the medical and dental applications of polyhydroxyalkanoates (PHAs), highlighting their potential for improving drug delivery and providing biocompatible solutions for medical devices, but reports no new clinical results.
15 citations
,
August 2023 in “Journal of Nanobiotechnology” This review highlights recent advancements in using nanotechnology for scar prevention and treatment, emphasizing the unique properties of nanomaterials in drug delivery and the challenges that remain in maximizing their potential for effective scar interventions.
15 citations
,
May 2013 in “International Journal of Cosmetic Science” This study found that while ethnic hair types share a common fibrous keratin structure, variations in keratin-associated proteins and lipids may lead to different macroscopic hair characteristics.
15 citations
,
August 2008 in “Plastic & Reconstructive Surgery” This review examines the emergence of new adult stem cell sources with potential for bone tissue engineering and discusses their advantages over traditional sources.
10 citations
,
November 2017 in “Letters in drug design & discovery” This paper discusses a structure-based analysis to find new BRD4 inhibitors, identifying finasteride and amentoflavone as promising candidates for BET inhibition.
10 citations
,
May 2012 in “Cell Adhesion & Migration” This study found that ILK/ELMO2 complexes in epidermal keratinocytes are selectively activated by epidermal growth factor to induce cell migration, unlike with other growth factors.
9 citations
,
August 2025 in “Current Issues in Molecular Biology” This review discusses the role of extracellular vesicles in bone regeneration and their potential as therapeutics, highlighting challenges like standardization and safety for clinical application, but it reports no new clinical results.
8 citations
,
September 2024 in “International Journal of Molecular Sciences” This review discusses how polymers can be customized to develop biomaterials that mimic the extracellular matrix, exploring their potential in biomedical and biotechnological applications by triggering cell functions similar to natural physiological systems.
8 citations
,
September 2023 in “International Journal of Nanomedicine” In this study, researchers developed an in vitro airway-organoid model using human lung-derived cell lines on RADA16-I hydrogels to serve as a potential tool for studying adenovirus isolation, pathogenesis, and antiviral drug screening.
8 citations
,
January 2023 in “RSC Advances” This article reviews advancements in carbon dots for tissue engineering and regenerative medicine, highlighting challenges and future directions without presenting new clinical findings.
6 citations
,
July 2025 in “Pharmaceuticals” This review highlights the promising biomedical applications of marine-derived polysaccharides, proteins, and peptides, particularly in drug delivery and wound healing. It discusses their potential as biomaterials in creating nanocarriers, hydrogels, and more, alongside fabrication strategies, regulatory challenges, and sustainability considerations.
6 citations
,
April 2025 in “Plastic and Aesthetic Research” This review highlights that biomaterial properties can be designed to modulate macrophage activity, potentially reducing foreign body responses and enhancing tissue healing in regenerative medicine.
6 citations
,
December 2022 in “Colloids and Surfaces B: Biointerfaces” This study reported that a novel bilayer wound dressing made from PLCL nanofibers and keratin hydrogel, loaded with FGF-2, promoted skin healing and showed potential for use in skin tissue engineering.
5 citations
,
November 2025 in “Cells” This review summarizes the roles of various cells and signaling pathways in skin wound healing, highlights deviations leading to pathological outcomes like chronic wounds, and evaluates cutting-edge approaches such as biomaterials and precision medicine to improve healing and intervention strategies.
5 citations
,
March 2024 in “Frontiers in Bioengineering and Biotechnology” In this study, researchers successfully constructed a high-precision three-dimensional model of human skin dermis, revealing a detailed analysis of dermal porosity and pore diameter distribution, which can aid the development of biomimetic tissue-engineered skin.
5 citations
,
January 2004 This paper describes the cellular and molecular processes involved in dermal tissue repair and reports no new experimental results.
3 citations
,
October 2025 in “Journal of Materials Science Materials in Medicine” This review discusses various biomedical applications of hyaluronic acid, highlighting its roles in cancer treatment, wound healing, inflammation control, antibiotics, and antioxidant functions, with an emphasis on recent developments and potential for advanced drug delivery and tissue repair systems.
2 citations
,
December 2013 in “Current Oral Health Reports” This review discusses current developments in tooth regenerative therapy, including bioengineered tooth replacements, and emphasizes its potential to fully restore tooth function, but it presents no new clinical results.
1 citations
,
February 2026 in “ACS Omega” This review highlights the potential of self-powered nanogenerators in revolutionizing biomedical devices by using biomechanical or environmental energy, focusing on applications like regenerative hair growth, drug release patches, and electronic skin while evaluating challenges such as energy efficiency and biocompatibility.