research Smad4-Dependent Desmoglein-4 Expression Contributes to Hair Follicle Integrity
Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.
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30 / 65 results research Minoxidil Cyclodextrin Complexes and Their Inclusion in Transfersomes for the Enhancement of Therapeutic Effect on Androgenic Alopecia
The new minoxidil formulation could better promote hair growth for treating androgenic alopecia.
research Type A Insulin Resistance Syndrome Due to a Novel Heterozygous c.3486_3503del (p. Arg1163_Ala1168del) INSR Gene Mutation in an Adolescent Girl and Her Mother
A new gene mutation causes insulin resistance in a girl and her mother.
research Persistent Erectile Dysfunction in Men Exposed to 5α-Reductase Inhibitors, Finasteride, or Dutasteride
Using finasteride or dutasteride may cause long-lasting erectile dysfunction.
research Experimental, Molecular Docking Investigations and Bioavailability Study on the Inclusion Complexes of Finasteride and Cyclodextrins
Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.
research Hormonal Implants, Beauty Chip: Benefits And Harmful Effects
Hormonal implants have many side effects that often outweigh their benefits.
research Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
research Adverse Side Effects of 5α-Reductase Inhibitors Therapy: Persistent Diminished Libido, Erectile Dysfunction, and Depression in a Subset of Patients
Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.
research The Harmonies Played by TGF-β in Stem Cell Biology
TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.
research Targeting Wnt/β-Catenin Pathway for Developing Therapies for Hair Loss
Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.
research Thyrotropin Releasing Hormone: A New Player in Human Hair Growth Control
TRH stimulates human hair growth and extends the hair growth phase.
research Tumor Regression Predicts Higher Risk of Sentinel Node Involvement in Thin Cutaneous Melanomas
Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.
research The Role of Smads in Skin Development
Smad-4 and Smad-7 are key in hair follicle development, with other Smads being less important.
research The Genetics of Hair Shaft Disorders
The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
research Evaluation of DNA Variants Associated with Androgenetic Alopecia and Their Potential to Predict Male Pattern Baldness
DNA variants can predict male pattern baldness, with higher risk scores increasing baldness likelihood.
research Adverse Event Reporting in Clinical Trials of Finasteride for Androgenic Alopecia: A Meta-Analysis
Finasteride for hair loss may cause long-lasting side effects like impotence and low libido, but trials lack proper safety reporting.
research Microneedle Arrays Combined With Nanomedicine Approaches for Transdermal Delivery of Therapeutics
Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.
research Binary and Ternary Inclusion Complexes of Finasteride in HPβCD and Polymers: Preparation and Characterization
Finasteride complexes with HPβCD and polymers improve solubility, potentially enhancing hair loss treatment.
research Evaluation of the Predictive Capacity of DNA Variants Associated with Straight Hair in Europeans
Certain DNA variants can predict straight hair in Europeans but are not highly specific.
research Antibody-Capped Mesoporous Nanoscopic Materials: Design of a Probe for the Selective Chromo-Fluorogenic Detection of Finasteride
Probe detects finasteride with high selectivity and low detection limit.
research Msx2 Supports Epidermal Competency During Wound-Induced Hair Follicle Neogenesis
The gene Msx2 is crucial for hair follicle regeneration during wound healing.
research A Preliminary Study of Differentially Expressed Genes in Expanded Skin and Normal Skin: Implications for Adult Skin Regeneration
The study found that expanded skin regenerates similarly to normal skin, with 77 genes playing a role in the process.
research Live Imaging of Smad2/3 Signaling in Mouse Skin Wound Healing
Smad2/3-dependent TGF-β signaling increases during wound healing.
research Psychoactive Drugs and Skin
Some psychoactive drugs can cause skin reactions, with carbamazepine having a higher risk, and stopping the drug and seeing a dermatologist is important.
research Androgen Receptor Activation Integrates Complex Transcriptional Effects in Osteoblasts, Involving the Growth Factors TGF-β and IGF-I, and Transcription Factor C/EBPδ
DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.
research Therapeutic Potential of Endogenous Stem Cells and Cellular Factors for Scar-Free Skin Regeneration
Using skin stem cells and certain molecules might lead to scar-free skin healing.
research Plasma Zinc Levels in Males with Androgenetic Alopecia as Possible Predictors of Conservative Therapy Effectiveness
Lower zinc levels may predict less effective hair loss treatment.
research Stem Cells of the Hair Follicular Tissue: Application in Cell-Based Therapy for Vitiligo
Hair follicle stem cells could be used to treat the skin condition vitiligo.
research SNP Variation in Male Pattern Hair Loss in Russians with Different Dihydrotestosterone Levels
Certain gene variations increase male hair loss risk, influenced by hormone levels.
research Recent Advances in Cellulose Nanocrystals-Based Sensors: A Review
Cellulose nanocrystals are promising for making effective, sustainable sensors for various uses.