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The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

TSH is usually the only test needed to check thyroid function in primary care.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

Minoxidil and finasteride can slow hair loss and stimulate regrowth, but won't restore all lost hair or reverse complete baldness.

Liposomes could improve how skin care products work but are costly and not very stable.

Giving a special protein to dogs with a certain genetic disease improved their symptoms but didn't help with hair growth.

The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

Minoxidil-loaded NLC gel shows potential for effective alopecia treatment.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Different soft tissue fillers can cause various skin reactions; biodegradable fillers are safer and non-biodegradable ones like silicone can lead to long-term problems.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Eating fewer calories, less sugar and refined carbs, and more low-glycemic and omega-3 rich foods can help manage PCOS symptoms.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

The document concludes that hirsutism is the main sign for diagnosing hyperandrogenism, which requires a detailed patient history and physical exam.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Fat tissue stem cells may help increase hair growth.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Smart biomaterials that guide tissue repair are key for future medical treatments.