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The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Dermoscopy is a useful tool for identifying features of skin conditions, but more research is needed to define its role in dermatology.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Dermatologists need to understand hair products to treat hair and scalp issues better.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.

New effective scar treatments are urgently needed due to the current options' limited success.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Baldness is more common in Chinese men than women, increasing with age, and is influenced by genetics.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.