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Brepocitinib 30mg is most effective for moderate-to-severe alopecia areata, but ritlecitinib 50mg may offer a better balance of safety and effectiveness.

Higher granulysin levels in the blood are linked to more severe hair loss in alopecia areata patients, and these levels decrease after effective treatment.

Some treatments for severe hair loss work but often have side effects, with baricitinib showing the most promise.

Baricitinib helps regrow hair in adults with severe alopecia better than a placebo and is approved for treatment, but long-term effects are still unknown.

Hair regrowth from severe alopecia areata treatment with baricitinib can vary, with faster results in those with shorter hair loss duration.

Ritlecitinib significantly improves scalp hair regrowth in alopecia areata patients over time.

Both tofacitinib and ruxolitinib are effective and tolerable for treating alopecia areata.

Oral tofacitinib may be an effective and tolerable treatment for some people with severe alopecia areata.

Traditional treatment for pediatric alopecia areata is most effective and should be first choice.

The trial showed that a new under-the-tongue treatment for severe hair loss was somewhat effective in a small group of people.

Oral JAK inhibitors are effective and safe for treating alopecia areata but may need ongoing use to keep results.

Tofacitinib is effective and safe for long-term treatment of severe alopecia areata, with many patients achieving complete hair regrowth.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Tofacitinib is somewhat effective for alopecia areata, but more research is needed on its safety and long-term effects.

No systemic treatment for alopecia areata has strong evidence of effectiveness.

1% anthralin ointment is effective and safe for treating severe alopecia areata in children.

Topical calcipotriol may help treat alopecia areata, especially in those with low vitamin D.

Baricitinib helps improve hair growth in severe alopecia, with better results in less severe cases and higher doses working faster.

Baricitinib is effective for severe alopecia areata but has some side effects.

Severe alopecia areata patients have a low chance of spontaneous hair regrowth.

Baricitinib is effective and safe for long-term use in severe alopecia areata, improving hair regrowth and quality of life with few side effects.

New treatments for alopecia areata show promise, but more research is needed to confirm their effectiveness.

Baricitinib helped some patients with tough-to-treat hair loss regrow hair, but more research is needed on its safety.

Tofacitinib was effective for severe, treatment-resistant hair loss without side effects.

Apremilast was not effective in treating moderate-to-severe alopecia areata.

Baricitinib is effective and safe for treating severe alopecia areata.

Tofacitinib works better and is more tolerable for severe alopecia than conventional treatments and DPCP immunotherapy.

Baricitinib and deuruxolitinib are effective for treating alopecia areata, but their efficacy depends on the dose.

JAK inhibitors help hair regrowth in alopecia areata but have a high risk of side effects.

Alopecia areata treatment varies, with no optimal method established yet.