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Children with severe ichthyosis and growth failure rarely have nutritional deficiencies or gastrointestinal issues, but may experience chronic dehydration.

There is a significant need for better-validated quality of life tools in dermatology.

People with Epidermolysis bullosa have many health problems including poor oral health, which is often neglected due to other medical issues.

ANA-negative lupus nephritis can be diagnosed and treated effectively with a comprehensive approach.

The document emphasizes the importance of ongoing research and ethical considerations in genome editing and cellular reprogramming.

Pattern baldness is likely caused by a dominant gene influenced by testosterone levels, making it more common in men.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

Most women with hirsutism have it because of PCOS, and they need long-term treatment including medication and hair removal to improve their condition.

New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.

Hair analysis can somewhat track past testosterone levels but is influenced by factors like hair washing, growth rate, sex, and hair color.

The spironolactone cream did not reduce hair growth in women with hirsutism.

Topical spironolactone cream doesn't cause hormone-related side effects in the body.

Men with moderate hair loss had the best spatial thinking, and long-term DHT might affect cognition.

Segmental hair analysis can track testosterone over time but needs adjustments for sex, hair color, and washing frequency.

Hair cortisol levels can show increased stress during late pregnancy but only for up to six months.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.

Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.

The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Using 17-hydroxyprogesterone levels to diagnose nonclassic congenital adrenal hyperplasia can result in many incorrect diagnoses.

Researchers developed a reliable method to measure testosterone and epitestosterone in urine for medical and anti-doping use.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Collecting hair for cortisol analysis is possible in low-income mother-toddler pairs.

Some supplements and hormones can increase hair loss by raising DHT levels.

Hair cortisol is a reliable stress indicator in cattle but may not be valid for pigs.

Beards and long hair may affect how attractive someone is to the opposite sex.

Pigs in farrowing crates and loose-housing systems showed no difference in chronic stress levels as measured by hair cortisol.