18 citations
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November 2017 in “International Journal of Cosmetic Science” This study found that Bio Skin Oil® reduced the appearance of non-keloid scars and striae, with significant improvements observed by both investigators and participants.
7 citations
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February 2022 in “International Journal of Pharmaceutics” In a mouse model of androgenetic alopecia, this study found that a safflower oil body nanoparticle loaded with human fibroblast growth factor 10 significantly improved hair regeneration and reduced associated microinflammation without significant toxicity.
3 citations
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February 2023 in “ACS omega” In this study, grape seed oil was found to be the most effective herbal oil for improving gloss and reducing fractures in various hair types.
12 citations
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August 2018 in “BMC Biotechnology” This study found that oil body bound oleosin-rhFGF9 expressed in safflower seeds stimulated hair growth and enhanced wound healing in mice by possibly up-regulating β-catenin expression.
In this study, ozonized sunflower oil effectively healed skin wounds in a dog and a cat over 30 and 50 days, respectively, with no side effects, showing faster hair regrowth and improved local metabolism.
June 2024 in “International Journal of Cosmetic Science” This study found that various plant oils can penetrate the lipid-rich cell membrane complex of hair, improving its fatigue strength by preventing flaw propagation, with greater penetration observed for oils containing shorter chain lengths and unsaturated fatty acids.
11 citations
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January 2006 in “International Journal of Cosmetic Science” Some oils can penetrate hair and reduce the stickiness between fibers, but mineral oil cannot.
August 2025 in “Deleted Journal” This article provides an overview of herbal oils or extracts, particularly focusing on the benefits of Arwa oil, which combines various natural oils to nourish hair follicles and treat scalp inflammation, potentially addressing hair problems like hair loss and split ends.
February 2024 in “Bangladesh pharmaceutical journal” In this study, researchers formulated a herbal hair oil with natural ingredients and reported that 56.25% of participants experienced increased hair growth and 50% had reduced hair fall after 3 months, without significant side effects.
In this study, six types of cold-pressed oils commonly found in the Polish market were analyzed for their health-promoting compounds and antioxidant activity, revealing them as valuable sources of bioactive compounds like polyunsaturated fatty acids, tocopherols, sterols, and polyphenols, without exceeding recommended deterioration parameters.
January 2026 in “Open Veterinary Journal” This study found that supplementing cat and dog food with PUFA-rich oil improved hair flexibility, brightness, and skin condition, though it also increased serum triglyceride levels, suggesting careful consideration of dosage and fatty acid composition is warranted.
1 citations
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March 2024 in “International Journal of Pharmaceutical Sciences and Drug Research” In this study on albino mice, Helianthus annuus and Martynia annua seed oil extracts in petroleum ether significantly promoted hair growth in a dosage-dependent manner, with 30 mg/ml showing notable results compared to 2% minoxidil.
January 2024 in “International Journal of Zoological Investigations” In this study, a herbal oil formulation containing extracts from Martynia annua and Helianthus annuus seeds showed greater potential for hair growth in albino mice compared to finasteride and minoxidil.
73 citations
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July 1977 in “Archives of Dermatology” In this case report, applying linoleic acid topically reversed essential fatty acid deficiency and related skin symptoms in a patient receiving long-term fat-free intravenous nutrition.
20 citations
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May 1985 in “British journal of nutrition” This study found that in genetically diabetic mice, supplementation with safflower or evening primrose oil prevented the decrease in certain fatty acids and improved skin conditions, but increased plasma glucose levels.
14 citations
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July 1977 in “PubMed” This study reported that a 19-year-old man's essential fatty acid deficiency was reversed with daily topical application of linoleic acid, improving clinical symptoms and normalizing certain fatty acid levels.
14 citations
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July 1977 in “Archives of Dermatology” This case report found that a linoleic acid topical application reversed essential fatty acid deficiency and improved scalp dermatitis, alopecia, and hair depigmentation in a 19-year-old patient on fat-free intravenous nutrition.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers formulated and evaluated a herbal hair serum using natural ingredients, with formulation H3 showing superior viscosity, homogeneity, and stability. The authors suggest it may be a safe and effective natural option for enhancing hair nourishment and health.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers developed and tested three formulations of a herbal hair serum containing ingredients like Aloe vera and rose water, finding that all formulations exhibited acceptable properties for scalp application, with the H3 batch shown to have superior viscosity, homogeneity, and stability.
May 2023 in “International journal of pharmaceutical sciences and medicine” This study found that Helianthus annuus oil promoted hair growth in a testosterone-induced alopecia mouse model, with higher hair density observed compared to untreated mice, though it was less effective than the standard minoxidil treatment.
January 2020 in “Acta Scientiae Veterinariae” In this case report, a combination of ozone therapy, low-level laser, and herbal medicine gel effectively improved healing in a dog with chronic bite wounds.
June 2025 in “Unram Medical Journal” This review found that linoleic acid, when used in various skincare product formulations such as creams and serums, offers potential benefits for skin regeneration and hair growth, highlighting its promise as a natural, sustainable ingredient in cosmetics.
20 citations
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September 2015 in “Protein expression and purification” This study demonstrated that safflower seeds can be engineered to express oleosin-FGF10, which showed a dose-dependent effect on cellular proliferation, potentially facilitating scalable protein production.
This study found that transgenic safflower oil bodies expressing oleosin-rhFGF9 promoted significant hair regrowth and wound healing in mice compared to control groups.
13 citations
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April 2017 in “Journal of Alternative and Complementary Medicine” This review discusses traditional and complementary medicine practices for skin health, examining existing literature and emphasizing the challenge of conducting research in these areas, without providing new clinical results.
June 2014 in “Basic & Clinical Pharmacology & Toxicology” This study found that alkaloids isolated from Cucumis metuliferus fruit pulp demonstrated antiviral activity against IBDV in chicken embryo fibroblast cells and NDV in 10-day-old embryonated chicken eggs, while being non-cytotoxic.
11 citations
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October 2017 in “International Journal of Molecular Sciences” In this study, oil body-bound oleosin-rhFGF-10 was more efficiently absorbed through the skin and enhanced wound healing and hair growth in mice, compared to prokaryotically-expressed rhFGF-10.
2 citations
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December 2021 in “ScienceRise” This study identified optimal parameters for extracting oil from Urtica dioica roots to maximize phytosterol content, using corn oil and a 1:5 raw material-extract ratio over a 6-hour maceration period.
December 2025 in “Revista em Agronegócio e Meio Ambiente” This study investigated the effects of ultrasound-assisted extraction on sunflower seed oil mixed with defective green coffee grains, finding that higher coffee grain ratios decreased oil yield but increased phenolic content and antioxidant activity, with potential applications for wound treatment.
January 2021 in “Journal of Scientific Research of the Banaras Hindu University” In this study of young adults in Angamaly, only 5% were found to have Polycystic Ovary Syndrome, with dietary choices playing an important role in symptom management.