research Short-Term Side Effects of Low Dose Valproate Monotherapy in Epileptic Children: A Prospective Study
Low dose valproate in epileptic children mainly causes weight gain and other non-life-threatening side effects.
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research Computational Drug Repositioning in Cardiorenal Disease: Opportunities, Challenges, and Approaches
Drug repositioning is a promising way to quickly develop new treatments, especially for rare diseases.
research The Safety of Testosterone Therapy in Women
Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.
research Evaluation of Efficacy, Safety, and Reversibility of Combination Regimen of Cyproterone Acetate and Testosterone Buciclate in Bonnet Monkeys
The right dosage of CPA and TB can work as a safe and reversible male contraceptive in monkeys.
research Safety and Effectiveness of a Novel Hyaluronic Acid Gel for Lip Augmentation
The new hyaluronic acid gel is as safe and effective for lip enhancement as the existing product.
research Clinical Efficacy and Safety of Low-Dose Flutamide Alone and Combined with an Oral Contraceptive for the Treatment of Idiopathic Hirsutism
Low-dose flutamide helps reduce excessive hair growth and is even more effective with birth control, without bad effects on blood fats.
research Oxiconazole Nitrate: Pharmacology, Efficacy, and Safety of a New Imidazole Antifungal Agent
Oxiconazole nitrate cream is effective and safe for treating various fungal skin infections.
research Assessment of Dysregulation of HERC6 and Essential Biological Processes in Response to Laser Therapy of Human Arm Skin
Laser therapy on human skin affects the HERC6 gene and related genes, influencing many cell processes and requiring careful safety measures.
research Sexual Dysfunction, Including Hypoactive Sexual Desire Disorder: Diagnosis and Treatment Recommendations
Testosterone therapy can improve sexual function in women but long-term safety is unclear.
research A Review on Phytochemical, Ethnomedical, and Pharmacological Studies on Genus Sophora, Fabaceae
The genus Sophora has compounds with potential health benefits and could lead to new drugs, but more research is needed to understand their effects and safety.
research Transmasculine Hormone Therapy: Dermatologic, Genital, Sexual, and Cardiovascular Effects and Safety Concerns
Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.
research Use of Ethinylestradiol/Drospirenone Combination in Patients with Polycystic Ovary Syndrome
The birth control combination of ethinylestradiol and drospirenone helps treat symptoms of polycystic ovary syndrome.
research Autologous Cell Therapy for Aged Human Skin: A Randomized, Placebo-Controlled, Phase I Study
RCS-01 therapy is safe and may improve skin structure by affecting gene expression.
research Novel Janus Kinase Inhibitors in the Treatment of Dermatologic Conditions
JAK inhibitors show promise for treating various skin diseases.
research Formulation and Evaluation of Valproic Acid Microemulsions for Enhanced Transfollicular Delivery in Guinea Pig Skin
Valproic acid microemulsions improve skin delivery compared to regular solutions.
research Alopecia Universalis: Partial Response to Tofacitinib
Tofacitinib partially improved hair regrowth in a patient with severe hair loss.
research Safety of Testosterone Use in Women
Short-term testosterone therapy in women seems safe with few mild side effects, but long-term effects need more research.
research Safety of Testosterone Treatment in Postmenopausal Women
Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.
research Safety Aspects of Androgen Treatment with 5α-Dihydrotestosterone
DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.
research Safety Assessment of Linum Usitatissimum (Linn.) Ingestion in New Zealand Rabbits
Prolonged linseed ingestion is safe for rabbits.
research The Safety of 52 Weeks of Oral DHEA Therapy for Postmenopausal Women
Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.
research Integrated Safety Analysis of Ritlecitinib, an Oral JAK3/TEC Family Kinase Inhibitor, for the Treatment of Alopecia Areata from the ALLEGRO Clinical Trial Program
Ritlecitinib is safe and well-tolerated for treating alopecia areata in patients aged 12 and older.
research Hair Loss Profiles and Ritlecitinib Efficacy in Patients with Alopecia Areata: Post Hoc Analysis of the Allegro Phase 2b/3 Study
Ritlecitinib effectively improves hair growth in alopecia areata patients, regardless of hair loss pattern.
research Automatic Artificial Hair Implant: Safety and Efficacy in Androgenetic Alopecia. A Prospective Study with a Highly Biocompatible Fiber
Implant safely and effectively treats hair loss.
research Influence of Dosing Time on the Efficacy and Safety of Finasteride in Rats
Dosing time affects finasteride's effectiveness and safety in rats.
research Circulating and Intraprostatic Sex Steroid Hormonal Profiles in Relation to Male Pattern Baldness and Chest Hair Density Among Men Diagnosed with Localized Prostate Cancers
Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.
research Serenoa Repens (Saw Palmetto) for Lower Urinary Tract Symptoms: The Evidence for Efficacy and Safety of Lipidosterolic Extracts. Part III
Saw palmetto may improve urinary symptoms with fewer sexual side effects compared to some medications.
research Epidermal Growth Factor, Innovation and Safety
Recombinant human epidermal growth factor is versatile, effective, and safe for long-term skin and mucosal treatments.
research Teriflunomide Efficacy, Safety, and Tolerability in Patients with Relapsing Forms of Multiple Sclerosis
Teriflunomide is effective and generally safe for treating relapsing multiple sclerosis, reducing relapse rates and disability progression.
research Long-Term Dutasteride Therapy in Men with Benign Prostatic Hyperplasia Alters Glucose and Lipid Profiles and Increases Severity of Erectile Dysfunction
Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.