This study analyzed the FDA Adverse Event Reporting System and found distinct safety signals and adverse event patterns among α1-blockers, 5α-reductase inhibitors, and tadalafil used in treating benign prostatic hyperplasia, emphasizing known risks and identifying potential new ones that require further study.
December 2024 in “http://isrctn.com/” MpowerTM may improve hair growth and satisfaction more than plain minoxidil, with mild side effects.
January 2026 in “British Journal of Dermatology” This study found that combined microneedling with minoxidil significantly improved hair count and diameter in patients with androgenetic alopecia compared to minoxidil alone, despite mild adverse events, and microneedling parameters like depth and duration did not significantly affect outcomes.
March 2025 in “Archives of Dermatological Research” This study found that combined microneedling with minoxidil significantly improved hair count and diameter in patients with androgenetic alopecia, although more mild adverse events were reported compared to minoxidil alone.
3 citations
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March 2017 in “Regulatory toxicology and pharmacology” In this study, aleglitazar and its metabolite M6 were evaluated for safety in non-clinical settings, revealing organ-targeting effects common to PPAR agonists but no significant tumor increase in rat carcinogenicity studies, supporting progression to Phase 3 clinical trials.
2 citations
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January 2012 This study found that SESA oil significantly improved hair and scalp ailments more than coconut oil, with no adverse reactions reported during the study period.
February 2026 in “Scientific Reports” This preclinical study found that Mesenchymal Stem Cell-derived Conditioned Media formulations were safe and effective in rat and mouse models for treating chemotherapy- and radiation-induced oral mucositis, demonstrating improved tissue regeneration and healing, most notably at higher concentrations.
March 2024 in “Birth defects research” This correspondence comments on a 2023 study by Nagaoka et al. regarding the maternal–fetal safety of an aqueous extract of Casearia sylvestris leaves in rats, but it does not provide new results or data.
January 2024 in “http://isrctn.com/” Teak leaf extract hair tonic was tested for hair growth and safety.
This study found that proretinal nanoparticles, applied topically, are safe and effective for penetration into hair follicles, enhancing retinoid biological activity in the skin while reducing irritation compared to conventional retinal formulations.
December 2012 in “International Journal of Phytomedicine” This study found that SESA oil and capsules were associated with decreased hair fall and increased hair regeneration in patients with alopecia, without any reported adverse reactions over three months.
4 citations
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June 2023 in “Frontiers in immunology” This study found that JAK inhibitors effectively improve alopecia areata outcomes, as indicated by SALT scores, but they were associated with an increased risk of adverse effects, with 921 out of 1508 patients experiencing adverse reactions.
4 citations
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May 2020 in “International Journal of Women's Dermatology” In this double-blind, randomized controlled trial, researchers found that cow placenta extract lotion was as effective as topical minoxidil 2% in increasing hair count for women with androgenetic alopecia over six months, though the mean increases in hair count were similar for both treatments.
September 2026 in “Russian Journal of Skin and Venereal Diseases” In this study, photodynamic therapy combined with platelet-rich plasma showed potential for greater efficacy than photodynamic therapy alone in treating androgenic alopecia, with both approaches improving hair density without serious side effects.
September 2025 in “Journal of Cosmetic Dermatology” Single-needle radiofrequency is effective and safe for treating facial sebaceous hyperplasia.
August 2025 in “http://isrctn.com/” The supplement may improve hair growth and skin health with some mild risks.
May 2025 in “International Journal of Biological and Pharmaceutical Sciences Archive” In an open-label clinical trial, this study found that applying Narasimham Hair Oil thrice weekly for 8 weeks significantly improved hair density, thickness, and scalp health among participants with hair thinning, with benefits persisting after treatment, and 95% reporting user satisfaction without adverse effects.
This study reported that Soulflower Rosemary Redensyl Hair Growth Serum (Tetragain™) significantly improved hair growth, increased hair thickness, reduced hair fall, and decreased graying over 120 days, with participants rating the treatment as effective and experiencing no adverse effects.
January 2025 in “International Journal of Trichology” This study found both topical spironolactone and topical minoxidil to be effective and safe treatments for female pattern hair loss, with mild to marked improvement observed over six months in both treatment groups, though more side effects were noted with minoxidil.
January 2025 in “International Journal of Medical Arts” This study found that a topical 1.0% sildenafil citrate solution significantly increased vellus and terminal hairs in women with female pattern hair loss without affecting hair thickness, suggesting it may be a promising treatment option.
January 2024 in “Dermatologic Therapy” This retrospective study found that oral tofacitinib significantly reduced the severity of alopecia areata in children, achieving over a 50% reduction in hair loss severity, though relapse occurred during treatment tapering, and mild adverse effects were noted.
January 2022 in “Turk Dermatoloji Dergisi” This placebo-controlled study found that topical procyanidin B2 significantly increased total and anagen hair counts in men with androgenetic alopecia over 16 weeks compared to placebo, suggesting it as an effective and safe treatment option.
January 2014 in “Anales Médicos de la Asociación Médica del Centro Médico ABC” This study suggests that a combination of topical minoxidil with oral finasteride or dutasteride promotes hair growth in treating androgenetic alopecia, with only minor safety concerns reported.
This study compared the safety and effectiveness of 5% cetosomal minoxidil to 5% alcohol-based minoxidil in Indian men with androgenetic alopecia, finding that cetosomal minoxidil had improved safety and similar efficacy, making it a potentially better option for those sensitive to alcohol-based formulations.
This article discusses androgenetic alopecia, emphasizing its prevalence across age groups and noting that it is the most common cause of hair loss in adolescents, but provides no new clinical results.
4 citations
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October 2000 in “Contraception” This study found that a regimen combining cyproterone acetate and testosterone buciclate induced reversible azoospermia in bonnet monkeys, highlighting its potential as an effective male contraceptive.
1 citations
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February 2017 in “PubMed” In this open-label study, 80% of participants with androgenetic alopecia showed improvement after taking the oral supplement Forti5® for 24 weeks, with significant increases in hair mass index and terminal hair count.
January 2025 in “The Egyptian Journal of Hospital Medicine” This study observed significant repigmentation in localized stable vitiligo lesions treated with oral baricitinib, with even more improvement when combined with topical tacrolimus, and reported no side effects.
July 2024 in “Forum Dermatologicum” This review evaluates various topical treatments for androgenetic alopecia but does not provide new clinical findings, emphasizing the need for selecting therapies with limited systemic side effects.
January 2024 in “Journal of Scleroderma and Related Disorders” This study concluded that autologous platelet-rich plasma is a safe and effective technique for improving aesthetic concerns such as contour defects, pigmentation issues, and indurated lesions.