69 citations
,
July 1997 in “Der Urologe” This study found that PRO 160/120 and Finasteride showed similar effectiveness in improving urinary symptoms and quality of life in patients with benign prostatic hyperplasia over 48 weeks.
14 citations
,
June 2014 in “World Journal of Urology” This study found that the herbal combination PRO 160/120 significantly improved nocturnal voiding frequency in patients with moderate-to-severe LUTS/BPH compared to placebo, with similar effectiveness to tamsulosin and finasteride.
3 citations
,
January 2019 in “Therapeutic advances in urology” This review concluded that WS PRO 160 I 120 mg, a herbal preparation, may be an effective and safer alternative to standard drugs for treating lower urinary tract symptoms in men with benign prostatic hyperplasia.
1 citations
,
January 2022 in “Food & Function” This study found that fruit extracts from certain Egyptian Sabal species demonstrated significant anti-androgenic activity and potential therapeutic effects against benign prostatic hyperplasia in rat models and cell lines.
2 citations
,
June 2017 in “ScienceRise” This study developed a mask-cream containing Sabal palm extract and Sophora japonica tincture for androgenic alopecia prevention and treatment, establishing optimal production techniques using a reverse emulsion method.
3 citations
,
February 2023 in “International Journal of Molecular Sciences” This review discusses the composition, preparation, and applications of autologous platelet and extracellular vesicle-rich plasma, highlighting its potential benefits and the need for further research, but it reports no new clinical findings.
August 2026 in “Biology Bulletin Reviews” This study found that extracts from Avicennia marina, Moringa oleifera, and Calotropis procera demonstrated strong antibacterial, antioxidant, and hair-growth-promoting properties, with A. marina showing the most pronounced effects.
This study reports the development of a natural hair conditioner incorporating herbs like flaxseed, turmeric, and fenugreek, demonstrating satisfactory physical characteristics, stability, and potential effectiveness as a cost-effective alternative to commercial chemical hair products.
1 citations
,
August 2023 in “International journal of pharmacy & integrated health sciences” This review discusses various bioactive elements in cosmeceuticals, highlighting their potential benefits, such as anti-aging effects and skin tone improvement, while noting the growing demand due to safety concerns and expanding market opportunities.
January 2014 in “UMS Institutional Repository (Universiti Malaysia Sabah)” This study found that Murraya koenigii extracts and compounds demonstrated potent antibacterial and cytotoxic activities, with notable effects against antibiotic-resistant strains and cancer cell lines, supporting its potential for further pharmacological investigation.
3 citations
,
August 2021 in “Uro” This review concludes that global literature supports the lipidosterolic extract of Serenoa repens as efficacious and safe for treating lower urinary tract symptoms, with some studies showing equivalence to common pharmacologic agents.
2 citations
,
July 2021 in “Uro” This review discusses the efficacy of the lipidosterolic extract of Serenoa repens for treating lower urinary tract symptoms and reports no new clinical results; the authors propose further examination of the existing literature and guidelines.
8 citations
,
August 2011 in “Journal of Medicinal Food” In this study, D-004 did not affect androgen-dependent development in rats exposed in utero, while finasteride caused significant changes in male offspring's androgen-dependent tissues.
January 2002 in “Journal of Toxicology-cutaneous and Ocular Toxicology” Botanical extracts are increasingly important in cosmetics and drugs for their effectiveness and safety, backed by traditional use and scientific evidence.
January 2026 in “Indus journal of bioscience research.” In this study, Hibiscus rosa-sinensis extract was used to formulate and evaluate herbal cosmetic creams for their antioxidant properties, stability, and effectiveness. The formulations demonstrated strong antioxidant potential, stability under various conditions, and favorable cosmetic qualities, suggesting HRS as a beneficial ingredient in skincare products.
1 citations
,
January 2018 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” This study found that a herbal shampoo and solution were more effective than placebo in reducing hair loss and improving hair growth in participants with androgenetic alopecia and telogen effluvium.
22 citations
,
August 2009 in “Evidence-based Complementary and Alternative Medicine” This study found that a composition including Serenoa repens extract and anti-inflammatory agents effectively suppressed inflammation-related gene expression in a keratinocyte model, suggesting a potential dual strategy for treating androgenetic alopecia.
125 citations
,
December 2016 in “Molecules” This review discusses the extraction, purification, modification, and biological activity of polysaccharides from Traditional Chinese Medicine and reports no new research findings.
January 2025 in “The World Journal of Men s Health” In this study, autologous intratesticular PRP injection was found to be a feasible and well-tolerated procedure with low complication rates and quick recovery, but the authors indicated that current evidence is insufficient to confirm its effectiveness for mTESE.
8 citations
,
January 2022 in “Burns and trauma” This review discusses the role of extracellular vesicles from specific skin cells in wound healing, emphasizing their potential in regenerative medicine and reporting no new experimental results.
September 2023 in “Medical lasers” In this study, using a shampoo with Morus alba root extract over 12 weeks increased hair density and shaft thickness in patients with mild to moderate non-scarring alopecia, with both investigators and participants noting visible improvements and moderate satisfaction.
11 citations
,
July 2020 in “International Journal of Ayurvedic Medicine” This study identified 26 bioactive compounds in the ethanol extract of Indigofera tinctoria leaves, which are linked to various therapeutic activities, supporting its traditional medicinal use in treating numerous health conditions.
2 citations
,
April 2024 in “Science & Technology Indonesia” In this study, extracts from the bark of Albizia saponaria, particularly the ethyl acetate fraction, showed significant antioxidant activity, potentially due to its high phenolic and flavonoid content, suggesting its usefulness as a source of antioxidants for pharmaceutical formulations.
January 2024 in “Journal of Natural Remedies” This study found that the petroleum ether extract of Solanum nigrum may promote hair regrowth in testosterone-induced hair loss in rats, as indicated by increased follicle density and anagen/telogen ratio.
98 citations
,
August 2004 in “BJU international” This review critically examines the current medical management strategies for BPH/LUTS and reports no new experimental results.
69 citations
,
December 2011 in “Journal of Ethnopharmacology” This study found that Carthamus tinctorius exhibited the strongest 5α-reductase inhibitory and hair growth promoting activities among evaluated Thai herbs, suggesting potential for developing alternative hair loss treatments.
40 citations
,
August 2018 in “Skin appendage disorders” This review examines complementary and alternative medicine for alopecia and finds limited support from robust clinical trials, highlighting the need for standardized studies to evaluate efficacy and safety.
33 citations
,
May 2013 in “Andrologia” This study identified several herbs, including Ganoderma lucidum and Urtica dioica, that showed promising 5α-reductase inhibitory activity suggesting potential use in managing androgenic disorders.
6 citations
,
March 2014 in “Herba Polonica” This article reviews treatment options for androgenetic alopecia, highlighting potential uses of plant materials, but reports no new clinical results.
September 2021 in “Medicina Estética Revista Científica de la Sociedad Española de Medicina Estética (SEME)” The treatment improved hair growth and thickness in most patients with minimal side effects.