Search

everythinglearnresearchcommunity

for

Search:↓

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Wnt ligands are crucial for hair growth and repair.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Stem cell niches support, regulate, and coordinate stem cell functions.

Blocking JAK-STAT signaling can lead to hair growth.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.

Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.

Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.

Hair shedding is an active process that could be targeted to treat hair loss.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Blocking IL-12/IL-23p40 helped reverse severe hair loss in patients.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.

A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.

The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.

RANK-RANKL signaling is essential for hair growth and skin health.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Psoriasis is linked to other autoimmune diseases and involves a specific inflammatory process.

Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.

Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.