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This study reports that a novel frameshift mutation in the HTRA1 gene in a CARASIL pedigree led to reduced HTRA1 protein and increased TGF-β1 expression, potentially causing severe CARASIL and peripheral small arterial disease.

This report suggests that tofacitinib may be beneficial for patients with nail disease unresponsive to other treatments.

This study found that Chinese female patients with systemic autoimmune diseases treated intravenously with cyclophosphamide were more likely to experience gastrointestinal discomfort, myelosuppression, and alopecia.

This review highlights that hormones significantly influence the wound healing process by coordinating cellular and molecular activities, and hormonal therapy is emerging as a promising treatment, with current research focusing on optimizing dosages and minimizing side effects.

This study found that the water extract of Bituminaria bituminosa demonstrated the highest antioxidant activity and α-glucosidase inhibition among tested extracts, but no cholinesterase or tyrosinase inhibition.

This case report highlights a 33-year-old female with systemic lupus erythematosus and refractory alopecia who experienced significant hair regrowth after treatment with tofacitinib, maintained even after glucocorticoid tapering over two years.

Hair loss can be reversed or even cured using advanced hair restoration techniques, with rare complications like swelling and bleeding.

In this study, ALA-PDT significantly reduced lipogenesis in an acne-like model by upregulating OLR1 and suppressing lipid accumulation, highlighting a potential therapeutic target.

This study found that Oriental melon leaf extracts promoted hair growth in a mouse model and cultured human hair follicles, suggesting potential use as a treatment for hair loss.

This study found that Placenderm®, a porcine placenta peptide, may promote hair follicle regeneration and enhance hair growth in mice by balancing growth-promoting and inhibitory factors.

This study concluded that catgut embedment combined with moxibustion and bloodletting may be more effective than finasteride for treating androgenic alopecia, possibly due to reductions in testosterone and the testosterone/estradiol ratio.

Leflunomide is more likely to help treat alopecia areata than cause it.

This study found that essence containing fermented Opuntia ficus-indica var. sarboten fruits and Lactobacillus rhamnosus promoted more significant hair growth in mice than minoxidil.

This study found that Katsuwonus pelamis heart hydrolysates promoted hair growth in human dermal papilla cells, a 3D hair follicle organoid model, and C57BL/6 mice, suggesting its potential as a bioactive hair growth ingredient.

In this study, oral administration of blue honeysuckle fruit extract was found to promote hair growth in mice by enhancing dermal papilla cell proliferation and activating β-catenin signaling, suggesting its potential use as a food or cosmetic product for hair regeneration.

Using a special solvent can make Cacumen Platycladi essential oil more effective for treating hair loss.

This study on C57BL/6 mice found that subcutaneous cholesterol injections significantly promoted hair regeneration by enhancing hair follicle stem cell proliferation, highlighting the role of the PKA-tyrosine hydroxylase-sympathetic nervous system pathway in this process.

This study developed and validated a sensitive HPLC–MS/MS method for detecting seven prohibited substances in cosmetic products.

This study found that using hollow mesoporous silica nanoparticles as carriers in a topical finasteride formulation significantly enhanced drug retention and hair regrowth in an AGA mouse model, suggesting a promising approach for treating androgenetic alopecia with reduced side effects.

In this study, researchers demonstrated that zero valence fluorescent gold nanoclusters can be biosynthesized in damaged skin and inhibit hair follicle regeneration by affecting the NFκB inflammatory response pathway, suggesting potential as a treatment for hypertrichosis related to skin injury.

This article discusses central centrifugal cicatricial alopecia, highlighting its prevalence, potential genetic factors, and management challenges, but reports no new clinical conclusions and calls for further research.

A rare benign skin tumor showed unusual features of sebaceous and sweat glands, important for correct diagnosis.

This study demonstrated that a c-Kit-CreER-driven mouse model confirms melanocyte stem cells as a genuine source of melanoma, paralleling human melanoma in heterogeneity and gene signatures.

In this study, researchers demonstrated that human hair follicle outer root sheath cells release ATP, serotonin, and histamine in response to mechanical stimulation, which subsequently activates surrounding sensory neurons.

This study suggests that combination drug therapy with spironolactone and either oral contraceptives or dexamethasone effectively manages unresponsive hirsutism, with eight of nine patients achieving satisfactory clinical responses.

This review found no evidence that DHEA improves quality of life or decreases menopausal symptoms in peri- and postmenopausal women, but it may slightly enhance sexual function compared to placebo.

This review summarizes a 15-year collaboration on the role of synaptic-like vesicles in mechanosensory nerve terminals and suggests potential therapeutic implications for conditions like hypertension and muscle spasticity.