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Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

Selenium might help with insulin resistance and cholesterol in PCOS, but more research is needed to confirm its benefits.

Retinoids can prevent skin cancer in high-risk people but have side effects and require more research on dosing and effectiveness.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Isotretinoin at a low dose for three months does not significantly affect hair growth.

Tretinoin boosts minoxidil's effect on hair loss by increasing enzyme activity.

Dermal EZH2 controls skin cell development and hair growth in mice.

Alitretinoin may cause irreversible hair curling as a side effect.

The document concludes that individualized treatment for malignant epithelial tumors is necessary and more research on metastatic squamous cell carcinoma treatments is needed.

The document concludes that more research is needed to create specific drugs for treating male pattern baldness.

Male pattern baldness is caused by certain cells in hair follicles and could potentially be treated by targeting a specific growth factor, TGF-β1.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

Isotretinoin may cause temporary, reversible facial hair growth in some women.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.

Ezh2 controls skin development by balancing signals for dermal and epidermal growth.

Dermal EZH2 controls skin cell growth and differentiation in mice.

Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.

Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.

A patient experienced long-lasting hair loss after using acitretin for psoriasis.

Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.

PPARγ is crucial for skin health but can have both beneficial and harmful effects.

Topical retinoids effectively improve photodamaged skin.

Vitamin D receptor knockout mice have significant motor impairments but no cognitive deficits.

Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.

GPRC5D is linked to the formation of hair, nails, and certain tongue areas.

Two siblings with a genetic mutation had a form of rickets that doesn't respond to vitamin D.

Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.

Vitamin D is important for bones, hair, blood pressure, and breast development.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.