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    Glossary Ruxolitinib

    medication that inhibits JAK enzymes to treat certain diseases

    Ruxolitinib, also known by the brand name Jakafi, is a medication that inhibits Janus kinase (JAK) enzymes, which are involved in the signaling pathways that regulate immune function and blood cell production. It is primarily used to treat conditions like myelofibrosis and polycythemia vera, and has shown promise in treating certain types of alopecia by modulating the immune response that attacks hair follicles.

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    Research 30 of 581

    1. Oral ruxolitinib induces hair regrowth in patients with moderate-to-severe alopecia areata JCI insight · 2016 · 196 citations
    2. Rapid skin repigmentation on oral ruxolitinib in a patient with coexistent vitiligo and alopecia areata (AA) Journal of the American Academy of Dermatology · 2015 · 157 citations
    3. Ruxolitinib for the treatment of severe alopecia areata Journal of the American Academy of Dermatology · 2018 · 37 citations
    4. Ruxolitinib protects skin stem cells and maintains skin homeostasis in murine graft-versus-host disease Blood · 2018 · 33 citations
    5. Two cases of alopecia areata treated with ruxolitinib: a discussion of ideal dosing and laboratory monitoring International Journal of Dermatology · 2017 · 25 citations
    6. Developing a JAK Inhibitor for Targeted Local Delivery: Ruxolitinib Cream Pharmaceutics · 2021 · 24 citations
    7. Complete Regrowth of Beard Hair with Ruxolitinib in an Alopecia Universalis Patient Skin appendage disorders · 2017 · 22 citations
    8. Unexpected Hair Regrowth in a Patient with Longstanding Alopecia Universalis During Treatment of Recalcitrant Dermatomyositis with the Janus Kinase Inhibitor Ruxolitinib Acta Dermato Venereologica · 2020 · 13 citations
    9. Ruxolitinib found to cause eyelash growth: a case report Journal of medical case reports · 2017 · 9 citations
    10. Various Applications of Tofacitinib and Ruxolitinib (Janus Kinase Inhibitors) in Dermatology and Rheumatology: A Review of Current Evidence and Future Perspective Dermatology practical & conceptual · 2022 · 8 citations
    11. The use of topical ruxolitinib 1.5% cream in frontal fibrosing alopecia: A case report JAAD Case Reports · 2024 · 6 citations
    12. Ruxolitinib 1.5% Topical Cream for the Treatment of Pediatric Alopecia Areata Journal of Drugs in Dermatology · 2024 · 4 citations
    13. Alopecia Universalis and Chronic Graft-vs-Host Disease Treated With Ruxolitinib JAMA Dermatology · 2018 · 4 citations
    14. Ruxolitinib Rescues Multiorgan Clinical Autoimmunity in Patients with APS-1 Journal of clinical immunology · 2023 · 2 citations
    15. Delayed granulomatous eruption of the nose associated with ruxolitinib JAAD case reports · 2020 · 2 citations
    16. Off‐Label Use of Topical Ruxolitinib in Dermatology: A Systematic Literature Review and Current Perspectives Experimental Dermatology · 2025 · 1 citations
    17. Ruxolitinib reverses alopecia areata via a triple mechanism: JAK-STAT inhibition, localized oxidative stress attenuation and selective apoptosis modulation Journal of Translational Autoimmunity · 2026
    18. Ruxolitinib: A novel molecule in the management of dermatological disorders Indian Journal of Skin Allergy · 2026
    19. Overcoming genetic drivers in alopecia areata: hair regrowth in a patient with <i>AIRE</i> gene mutation (autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy, APECED syndrome) treated with ruxolitinib Clinical and Experimental Dermatology · 2026
    20. A Successful Treatment of Alopecia Universalis with Ruxolitinib Journal of Dermatology & Dermatologic Surgery · 2026
    21. A Single Subcutaneous Dose of BMD-1141 Stimulates Hair Regrowth Comparable to Daily, High-Dose Ruxolitinib in a Mouse Model of Alopecia Areata. PubMed · 2025
    22. BH02 Overcoming genetic drivers in alopecia areata: hair regrowth in a patient with the <i>AIRE</i> gene mutation treated with ruxolitinib British Journal of Dermatology · 2025
    23. Topical Ruxolitinib in Combination with Oral Minoxidil Results in Hair Regrowth in a Patient with Central Centrifugal Cicatricial Alopecia and Concomitant Traction Alopecia JAAD Case Reports · 2025
    24. ISID1108 - Comparison of ruxolitinib and a collagen-targeted PTH-based hair cycle stimulant on hair follicle counts and hair growth in the C3H/HeJ engrafted mouse model of alopecia areata. 2023
    25. 1108 Comparison of ruxolitinib and a collagen-targeted PTH-based hair cycle stimulant on hair follicle counts and hair growth in the C3H/HeJ engrafted mouse model of alopecia areata 2023
    26. Topical Ruxolitinib for the Treatment of Alopecia Universalis JAMA dermatology · 2015 · 96 citations
    27. A Case of Topical Ruxolitinib Treatment Failure in Alopecia Areata Journal of cutaneous medicine and surgery · 2017 · 30 citations
    28. Topical Ruxolitinib for Folliculitis Decalvans International Journal of Dermatology · 2026
    29. Fast clinical response with topical ruxolitinib in the management of non-segmental vitiligo detected by VISIA<sup>®</sup> analysis system Dermatology Reports · 2025
    30. Treatment of vitiligo with the topical Janus kinase inhibitor ruxolitinib: A 32-week open-label extension study with optional narrow-band ultraviolet B Journal of the American Academy of Dermatology · 2018 · 74 citations