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    Glossary Russell's sign

    presence of knuckle calluses from self-induced vomiting

    Russell's sign refers to the presence of calluses or scars on the knuckles or back of the hand, typically caused by repeated self-induced vomiting. This physical sign is often associated with bulimia nervosa, as individuals may use their fingers to induce vomiting, leading to abrasions from contact with their teeth.

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    1. Skin signs in anorexia nervosa Dermato-endocrinology · 2009 · 48 citations
    2. Cutaneous Manifestations of Eating Disorders Journal of Cutaneous Medicine and Surgery · 2002 · 48 citations
    3. Cutaneous Manifestations of Eating Disorders Journal of Cutaneous Medicine and Surgery · 2002 · 33 citations
    4. Is there a role for dermatologists in eating disorders? Expert Review of Dermatology · 2007 · 5 citations
    5. Why Evolution is Better than Revolution The American Journal of Cosmetic Surgery · 1997
    6. Self-cured Flank Alopecia in a Dog The Japanese Journal of Veterinary Dermatology · 2012
    7. Canonical prolactin signaling and global mRNA expression in the skin of Holstein heifers carrying the SLICK1 allele of the prolactin receptor gene Journal of Dairy Science · 2025 · 1 citations
    8. Pharmacological Mobilization of Endogenous Stem Cells Significantly Promotes Skin Regeneration after Full-Thickness Excision: The Synergistic Activity of AMD3100 and Tacrolimus Journal of Investigative Dermatology · 2014 · 49 citations
    9. Novel recombinant human acid α-glucosidase with optimal glycosylation is significantly better than standard of care enzyme replacement for glycogen clearance in skeletal muscles of GAA knock-out mice Molecular Genetics and Metabolism · 2015 · 5 citations
    10. MON-218 Inflammatory Role of Sex Steroids in Hidradenitis Suppurativa: An Androgenic Phenotype Journal of the Endocrine Society · 2019
    11. mTOR signaling promotes stem cell activation via counterbalancing BMP-mediated suppression during hair regeneration 2015 · 71 citations
    12. Regulation of masculinization: androgen signalling for external genitalia development Nature Reviews Urology · 2018 · 45 citations
    13. β-Catenin–Dependent Wnt Signaling: A Pathway in Acute Cutaneous Wounding [RETRACTED] Plastic and Reconstructive Surgery · 2018 · 13 citations
    14. Darier Sign: A Historical Note Archives of Dermatology · 2002 · 5 citations
    15. A Signature of Genes Featuring FGF11 Revealed Aberrant Fibroblast Activation and Immune Infiltration Properties in Keloid Tissue Emergency medicine international · 2022 · 2 citations
    16. Role of the Wnt signaling pathway in keratoacanthoma Cancer reports · 2019 · 2 citations
    17. Co-opting Developmental Signaling Pathways to Promote Wound Healing Recent clinical techniques, results, and research in wounds · 2018 · 1 citations
    18. MicroRNA control of signal transduction Nature Reviews Molecular Cell Biology · 2010 · 1066 citations
    19. Signaling in the stem cell niche: regulating cell fate, function and plasticity Development · 2018 · 139 citations
    20. Significance of iron status in hair loss in women British Journal of Dermatology · 2003 · 5 citations
    21. Circulating MicroRNA Signatures in Severe Alopecia Areata: Diagnostic Discrimination, Pathway Analysis, and Therapeutic Implications Dermatology and Therapy · 2026
    22. Signaling pathways in hair aging Frontiers in cell and developmental biology · 2023
    23. A 12-week treatment with the long-acting glucagon-like peptide 1 receptor agonist liraglutide leads to significant weight loss in a subset of obese women with newly diagnosed polycystic ovary syndrome Hormones · 2015 · 61 citations
    24. AUSTRALIAN TRIAL OF TOPICAL MINOXIDIL AND PLACEBO IN EARLY MALE PATTERN BALDNESS Australasian Journal of Dermatology · 1990 · 11 citations
    25. Cyclooxygenase-2 overexpression in the skin of transgenic mice results in suppression of tumor development. PubMed · 2002 · 113 citations
    26. Intraretinal variation in disease severity in the Oat mouse model of gyrate atrophy Experimental Eye Research · 2025
    27. The Pathobiology of Skin Aging American Journal Of Pathology · 2020 · 122 citations
    28. Dermatologic Signs in Patients with Eating Disorders American Journal of Clinical Dermatology · 2005 · 130 citations
    29. Mesenchymal–epithelial interactions during hair follicle morphogenesis and cycling Seminars in Cell & Developmental Biology · 2012 · 300 citations
    30. Fibroblast heterogeneity: implications for human disease Journal of Clinical Investigation · 2018 · 299 citations