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    Glossary RUNX1

    regulates gene expression crucial for blood cell development

    RUNX1, also known as Runt-related transcription factor 1, is a gene that plays a crucial role in the regulation of gene expression during the development of blood cells. Mutations in RUNX1 are associated with various blood disorders, including acute myeloid leukemia (AML), making it a significant focus in both clinical and research settings.

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    Research 30 of 429

    1. New insights into the role of Runx1 in epithelial stem cell biology and pathology Journal of Cellular Biochemistry · 2012 · 63 citations
    2. Dynamic expression of Runx1 in skin affects hair structure Mechanisms of Development · 2006 · 46 citations
    3. Runx3 is involved in hair shape determination Developmental dynamics · 2005 · 34 citations
    4. Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and Scd1 and Soat1 Activity Stem cells · 2018 · 24 citations
    5. Runx Family Genes in Tissue Stem Cell Dynamics Advances in Experimental Medicine and Biology · 2017 · 6 citations
    6. Runx1 transcription factor is involved in the regulation of KAP5 gene expression in human hair follicles Journal of dermatological science · 2006 · 6 citations
    7. 3D bioprinted GelMA scaffolds loaded with Runx2 overexpressed BMSCs for bone regeneration Materials & Design · 2026
    8. Aconiti Lateralis Preparata Radix Activates the Proliferation of Mouse Bone Marrow Mesenchymal Stem Cells and Induces Osteogenic Lineage Differentiation through the Bone Morphogenetic Protein-2/Smad-Dependent Runx2 Pathway Evidence-based Complementary and Alternative Medicine · 2013 · 18 citations
    9. A matter of life and death: self‐renewal in stem cells EMBO Reports · 2012 · 150 citations
    10. Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing Cell stem cell · 2020 · 128 citations
    11. Epidermal patterning and induction of different hair types during mouse embryonic development Birth defects research · 2009 · 81 citations
    12. <i>NUDT15</i>,<i>FTO</i>, and<i>RUNX1</i>genetic variants and thiopurine intolerance among Japanese patients with inflammatory bowel diseases Intestinal Research · 2017 · 40 citations
    13. GRHL3 binding and enhancers rearrange as epidermal keratinocytes transition between functional states PLOS Genetics · 2017 · 38 citations
    14. Cutaneous Retinoic Acid Levels Determine Hair Follicle Development and Downgrowth 2012 · 31 citations
    15. Molecular mechanisms of Y chromosome loss and <i>UTY</i> gene activity Future science OA · 2024
    16. Understanding The Molecular Mechanisms Of Hair Follicle Stem Cell Quiescence And Genome Plasticity eCommons (Cornell University) · 2013
    17. Epidermal Wnt/beta-catenin signalling promotes dermal adipocyte differentiation during hair follicle morphogenesis and regeneration Journal of Dermatological Science · 2012
    18. A molecular wound response program associated with regeneration initiation in planarians Genes & Development · 2012 · 212 citations
    19. Identification of potential key genes and pathways associated with the Pashmina fiber initiation using RNA-Seq and integrated bioinformatics analysis Scientific Reports · 2021 · 36 citations
    20. Lithium chloride promotes the odontoblast differentiation of hair follicle neural crest cells by activating Wnt/β‐catenin signaling Cell Biology International · 2014 · 16 citations
    21. Androgen receptor activation integrates complex transcriptional effects in osteoblasts, involving the growth factors TGF-β and IGF-I, and transcription factor C/EBPδ Gene · 2015 · 11 citations
    22. <i>Ishige sinicola</i> extract stimulates osteoblast proliferation and differentiation via the bone morphogenetic protein 2/runt-related gene 2 signalling pathway Zeitschrift für Naturforschung C · 2019 · 4 citations
    23. Deciphering gene regulatory programs in mouse embryonic skin through single-cell multiomics analysis Genome biology · 2025
    24. Part 1. Genetic pathway of maternal transmission in Topiramate-treated zebrafish modelPart 2.Effects of herbal medicine on zebrafish embryos Spectrum Research Repository (Concordia University) · 2019
    25. Genome-Wide Association Study for Body Conformation Traits in Kazakh Fat-Tailed Coarse-Wool Sheep Genes · 2025 · 1 citations
    26. Adipose-derived stem cell exosomes promote critical-sized bone defect repair by enhancing the homing of bone marrow mesenchymal stem cells 2026
    27. Ionizable Coenzyme‐Engineered Lipid/Fiber Microplexes Boost Ribosomal Translation to Improve mRNA Therapy for Degenerative Diseases Advanced Materials · 2025
    28. 1469 Tissue mechanics partake in spatiotemporal patterning of wound-induced hair neogenesis in African spiny mouse Journal of Investigative Dermatology · 2018
    29. Fabrication and Characterization of 3BDO-Loaded Dissolvable Microneedle Patches for Hair Regrowth in C57BL/6 Mice Journal of Visualized Experiments · 2026
    30. Glucose-Activated Nanoreactor Initiating Cascade Reaction to Remodel Immune Microenvironment for Promoting Diabetic Wound Healing ACS Applied Materials & Interfaces · 2026