Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study identified a new subset of Ret-positive sensory neurons involved in itch perception, characterized by their unique expression profile and response to specific itch-inducing molecules.

Repetin is a protein involved in skin and hair development, binding calcium and compensating for other proteins when needed.

This study identifies specific molecular components involved in the intracellular trafficking of LGR5, revealing mechanisms that differ from typical GPCR recycling processes.

This study suggests that the interaction between folliculin and plakophilin-4 (p0071) may play a role in folliculin's tumor suppressor function by regulating RhoA signaling, impacting cell migration and junction formation.

In this study of mouse hair follicles, Raptor was specifically expressed in hair follicle stem cells, while Rictor was mainly found in inner root sheath cells, indicating distinct roles in hair growth stages.

This study reports that trichocyte intermediate filaments from rat vibrissae and human hair follicles may contain a hollow region at their core, suggesting unique structural properties.

This study observed that methylene blue staining and zinc iodide-osmium tetroxide techniques effectively revealed anatomical details of intraepidermal nerve fibre endings in the rat's mystacial pad, suggesting their potential role in mechanoreception.

This study found that methylene blue staining may reveal anatomical details of intraepidermal nerve fibre endings in the rat mystacial pad with greater clarity than the zinc iodide-osmium tetroxide technique.

This study suggests that Ptprq in the hair bundles may exist as multiple isoforms that are differentially expressed throughout development and affect the organization of stereocilia in the chick inner ear.

This study found that Piezo2 channels are primarily located on sensory axon membranes in mechanosensory end organs, supporting a model where mechanical stimuli activate Aβ RA-LTMR neurons via axon protrusions.

The researchers reported that mast cell and nerve fiber interactions in mouse skin are highly selective for nerve fiber types and vary depending on the hair cycle phase.

In this study, researchers observed that P2X3-immunoreactive fibers extensively innervate the epidermis of rats, suggesting a primary role in detecting noxious stimuli in cutaneous tissue.

This study found that RAR-gamma 1 mRNA is present in multiple skin layers and structures, suggesting a role in maintaining and differentiating normal epidermis and skin appendages.

This study concluded that terminal Schwann cells are essential for the maintenance and regeneration of mechanosensory lanceolate complexes at hair follicles in adult mice.

This study suggests that varying intersheet interactions may explain the differences between the two polymorphic forms of macrofibril assembly in Merino wool and hair.

This case report identifies a new type of hair matrix tumor called "rippled pattern trichomatricoma," distinguished by its unique cell arrangement and differentiation features.

This study found that Rac1 activity in specific skin compartments is sufficient for hair formation, but results in hair with altered structure and pigmentation compared to normal.

This study found that GFRα2 influences cell size but not survival or target innervation of Ret-positive low-threshold mechanoreceptors in mouse dorsal root ganglia, differing from its role in nonpeptidergic nociceptors.

This study revealed the complex three-dimensional innervation of touch domes in cat forepaw skin, highlighting the extensive branching and unmyelinated endings associated with Merkel cell–axon complexes.

This study found that cellular retinoic acid-binding proteins and fatty acid-binding proteins are dynamically expressed in skin development and respond differently to retinoic acid, β-catenin, and Notch signaling.

Retinoic acid receptors are important for hair follicle development.

This study observed that innervation of the mystacial pad in rats by fine-caliber axons is more extensive and complex than previously described, with distinct differences in labeling patterns depending on the tracer and survival time.

This study details the presence of two types of cysts in rhino mouse skin, with utricles derived from hair canals and deeper cysts from hair root sheath epithelium.

mTORC2 is crucial for healthy skin barrier by regulating lipids and filaggrin.

This study found that in mice, competition for hair follicles guides the organization of follicle-innervating LTMR neurons during early development, with different neuronal subtypes showing varying adaptive responses to increased neuron populations.

This study identified a subtype of itch-sensing neurons in mice, which express Ret and somatostatin, and found that their ablation reduces scratching induced by certain pruritogens.