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Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Cavity macrophages gather on organ surfaces but don't really invade or help repair the organs after injury.

DNA methylation and long non-coding RNAs are key in controlling hair growth in Cashmere goats.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

Hyaluronic acid-based HA2 hydrogel helps heal skin wounds better with less scarring.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

C-reactive protein helps monocytes stick to blood vessel cells by causing oxidative stress.

Four patients with a type of rickets and hair loss had different mutations in their vitamin D receptor gene, causing it to not work properly.

The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

DHT stops hair regrowth in mice, similar to human hair loss.

Adding human blood vessel cells to hair follicle germs may improve hair growth and quality.

Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.

Baicalin helps hair growth by activating specific cell signals and pathways.

The research suggests that a specific skin gene can be controlled by signals within and between cells and is wrongly activated in certain skin diseases.

Activating ER-β, not ER-α, improves skin cell growth and wound healing.

Wnt1a helps keep cells that can grow hair effective for potential hair loss treatments.

Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.

A specific protein in chicken embryos links early skin layers to feather development.

Cells treated with Wnt-10b can grow hair after being transplanted into mice.

Adiponectin may stimulate hair growth and could be a potential treatment for promoting hair growth.

Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Rice bran extract might help prevent hair loss.

The composition with carnitine, thioctic acid, and saw palmetto extract may effectively reduce inflammation in hair follicle cells.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

A specific gene change plus an additional mutation in the same gene cause hereditary trichilemmal cysts.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.