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This study found that albumin-bound paclitaxel combined with nedaplatin shows promise as neoadjuvant therapy for esophageal squamous cell carcinoma, achieving a high complete response rate with manageable side effects.

This study found that in estrogen receptor-positive breast cancer cells, 17β-estradiol repressed polyamine oxidase transcription by interacting with AP-1 sites on its promoter.

This study analyzed the transcriptome of the Tianzhu white yak, identifying differential transcripts that shed light on the molecular mechanisms influencing hair length growth variation in this species.

In this study, researchers observed that nestin-expressing cells in mice can differentiate into blood-vessel-like and nerve-like structures within human melanoma tumors, while bevacizumab treatment altered the origin of these structures to trans-differentiated melanoma cells without significantly impacting tumor growth.

This study found that modifying biphasic calcium phosphate/poly(methyl methacrylate) bone cement with human hair keratin improves its hydrophilicity, mechanical properties, and supports bone repair in rats, indicating potential for orthopedic applications.

This study found that elevated tissue RBP4 levels correlate with disease severity in alopecia areata and decrease after effective baricitinib treatment, while the rs3758539 polymorphism is linked to disease susceptibility but not to treatment response.

This study found that castration-resistant prostate cancers resistant to CYP17A1 inhibitors may still depend on steroids and could respond to therapies targeting de novo intratumoral steroid synthesis.

This study reported that pathways related to apoptosis, cell proliferation, and WNT signaling might be key drivers of hair loss in androgenetic alopecia, guiding potential targets for therapy development.

In this case report, a 5-year-old female German shepherd diagnosed with canine babesiosis and ehrlichiosis fully recovered after receiving parenteral treatment for these infections and topical therapy for dermatitis at the University of Ilorin's Veterinary Teaching Hospital.

This study suggests that the GPX-PDE1 and GPX-PDE2 genes in white lupin enhance root hair development and contribute to Pi limitation acclimation by facilitating glycerophosphodiester degradation.

This study identified a novel recessive mutation in mice causing lethal congenital lamellar ichthyosis, with skin and hair follicle alterations similar to human congenital ichthyoses, linked to a specific genetic defect affecting Fatp4.

In this study, UCMSC exosomes showed protective effects against cisplatin-induced hearing loss in mice by improving hearing and promoting cochlear tissue repair.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

This study found that Ldh activity in hair follicle stem cell-mediated squamous cell carcinoma is not necessary for tumorigenesis, as its modulation did not affect the cancer's development or characteristics.

This study found that the p63 transcription factor plays a role in epidermal morphogenesis by regulating Satb1 expression, impacting chromatin architecture and gene expression in epidermal progenitor cells.

This study found that while male COVID-19 patients in Brazil exhibited more severe symptoms and required more intensive care than females, the difference in risk of death was relatively small.

In this study, researchers found that human fingerprint ridges are formed through a modified hair follicle developmental process and spatial patterns influenced by specific signaling pathways.

This study found that early biochemical screening and molecular confirmation are crucial for distinguishing profound from partial biotinidase deficiency, which supports timely treatment and management in symptomatic children.

This review discusses various microneedle technologies for long-acting drug delivery, highlighting design considerations and challenges in bringing these minimally invasive devices to market, but it reports no new clinical results.

In this study, researchers found that p75 neurotrophin receptor signaling affects apoptosis during hair follicle regression in mice, and altering its activity might help manage disorders involving early catagen entry.

This study found that substance P may be involved in the pathogenesis of acne by increasing the expression of certain cytokines and receptors in cultured sebocytes.

This study identified somatostatin as a potential secretory factor contributing to the immune privilege of human hair follicles.

This study found that human outer root sheath cells express VEGF receptor-2, and exogenous VEGF165 significantly stimulates their proliferation through activation of the ERK signaling pathway.

This study found that Avicennia marina extract significantly inhibited 5α-reductase type 1 activity in human hair dermal papilla cells, suggesting its potential use for treating androgenic alopecia.

In this study, treatment with finasteride altered the expression patterns of antioxidant enzymes in the epididymis of rats, potentially affecting its protective function for spermatozoa.

No genetic link between prostaglandins and hair loss found.

This abstract lacks results; it aims to understand hair follicle regulation mechanisms but does not report specific findings or data.

This letter reports a woman with nevoid basal carcinoma syndrome and pronounced androgenic alopecia associated with a novel PTCH gene mutation p.Leu1159fsx32, suggesting a genetic link in this case study.

Protease Nexin-1 is found in human hair growth cells and is affected by male hormones.

Progranulin overexpression leads to shorter, thinner hair and increased cell death in mouse hair follicles.