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Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

Sphynx cats are hairless and Devon Rex cats have curly hair due to specific genetic mutations.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.

Prolactin affects when mice shed and grow hair.

TRH stimulates human hair growth and extends the hair growth phase.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

Tiny needles with valproic acid can effectively regrow hair.

Msx2 and Foxn1 are both crucial for hair growth and health.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Inactive hair follicle stem cells help prevent skin cancer.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

The gene Foxq1, controlled by Hoxc13, is crucial for hair follicle differentiation.

Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.

Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Technique creates 3D cell spheroids for hair-follicle regeneration.

Low-level laser therapy is safe and can increase hair growth for male and female pattern hair loss.

Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.

RANK-RANKL signaling is essential for hair growth and skin health.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

The TRPV3 gene mutation affects hair growth by keeping mice in the growth phase longer, which could help treat hair loss.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.