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Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.

Some common medications can harm male fertility, but many effects can be reversed.

Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.

Chemotherapy often causes skin, nail, and hair side effects, significantly impacting quality of life.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Imiquimod 5% cream reduced equine sarcoids in most cases.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Sphynx cats are hairless and Devon Rex cats have curly hair due to specific genetic mutations.

Certain medications including flutamide, spironolactone, and others effectively reduce excessive hair growth in women, especially when combined with lifestyle changes.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.

Toxic epidermal necrolysis is a severe skin condition often caused by drugs, with complex treatment and a high risk of death, but survivors usually heal without scars.

Biotin treatment can significantly improve hair loss and motor functions in certain metabolic disorders.

The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

The HR protein's role as a repressor is essential for controlling hair growth.

The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.

Prolactin affects when mice shed and grow hair.

Adult human skin can grow new fine hair follicles after a deep exfoliation treatment.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.