667 citations
,
May 2008 in “Genes & Development” This review discusses the biochemical and biological functions of histone demethylases and their potential involvement in human diseases, including cancer, but reports no new findings.
70 citations
,
February 2015 in “Expert Opinion on Drug Discovery” This review discusses current knowledge on the biological mechanisms of different types of alopecia but reports no new clinical findings; the authors highlight future research directions, especially regarding epidermal stem cells and immune pathways.
68 citations
,
July 2016 in “Dermatology and Therapy” This review highlights that light and laser therapies, such as the 1064-nm Nd:YAG and 810-nm diode lasers, may offer significant improvement for acne keloidalis nuchae with minimal side effects, though larger trials are needed.
68 citations
,
January 2008 in “Seminars in reproductive medicine” This narrative review discusses the impact of polycystic ovary syndrome on women's psychological and sexual well-being, highlighting the potential benefits of interdisciplinary treatments and new interventions to improve life satisfaction and coping, but reports no new results.
62 citations
,
September 1974 in “Academy of Management Journal” This article discusses the need for organizational scholars to shift focus from big business organizations to everyday events and places, but it reports no new empirical results.
58 citations
,
January 2006 in “Skin Pharmacology and Physiology” This study found that testosterone and 5α-dihydrotestosterone induced apoptosis in dermal papilla cells from nonbalding scalp regions, suggesting a high androgen stimulus can trigger cell death related to androgenetic alopecia.
53 citations
,
January 2017 in “BioMed research international” This review discusses the importance of omega-3 fatty acids for human health and explores recent advancements in genetically modifying plants to produce these essential nutrients, but reports no new results.
42 citations
,
March 2008 in “Molecular and Cellular Endocrinology” This review explores the potential (neuro-)endocrine influences on hair follicle epithelial stem cell biology and emphasizes the need for more systematic research, but it provides no new empirical results.
38 citations
,
November 2012 in “Expert Opinion on Drug Safety” This article reviews different acne treatments and emphasizes the importance of being aware of their potential side effects, but reports no new clinical results.
36 citations
,
June 2019 in “eLife” This study introduces MicrobeFDT, a tool that clusters chemically similar compounds and links them to gut microbial enzymes and toxicities, demonstrating its utility by uncovering previously unknown metabolism of the cancer drug altretamine.
30 citations
,
January 2009 in “Nuclear Receptor Signaling” This study identified the Hairless (Hr) gene-encoded protein as a corepressor that plays a crucial role in maintaining skin and hair by regulating epithelial stem cell differentiation and gene expression via chromatin remodeling, which may impact both development and disease.
24 citations
,
May 2012 in “International Journal of Dermatology” This review discusses the various causes and associations of eyelash trichomegaly, including congenital syndromes, acquired conditions, and drug effects, without reporting new clinical results.
10 citations
,
January 2014 in “Indian Dermatology Online Journal” This study found that skin disorders, particularly cosmetic issues like acne and hair loss, are very common among medical students, with gender and place of origin significantly influencing the development of certain conditions.
7 citations
,
June 2016 in “Bone Research” In this study, a Chinese Han family with hereditary vitamin D-resistant rickets was found to have a homozygous missense mutation in the VDR gene, and the affected individual uniquely responded well to treatment with oral calcium and low-dose calcitriol.
5 citations
,
May 2023 in “Frontiers in immunology” This review discusses how environmental factors like lifestyle, nutrition, and vitamin deficiencies may influence autoimmune diseases such as MS, SLE, and AA, highlighting associations with vitamin D levels and dietary interventions, but notes a lack of conclusive evidence for their roles in disease pathogenesis.
5 citations
,
November 2021 in “History & Philosophy of the Life Sciences” This article explores how narratives around racial and ethnic minorities versus fat individuals during the Covid-19 pandemic influenced the framing of these groups as "at-risk," with disparities in blame and responsibility linked to structural racism and anti-obesity rhetoric.
5 citations
,
November 2011 in “Expert Review of Dermatology” This review discusses the causes, diagnosis, and treatment of pediatric alopecia, emphasizing early diagnosis and considering holistic approaches, but reports no new clinical results.
4 citations
,
December 2013 in “Acupuncture and related therapies” This review summarizes the potential of N-acetyl-cysteine in managing diseases linked to redox imbalance, discussing its effects from cellular mechanisms to clinical applications, though further research is suggested for broader use.
4 citations
,
January 1994 This article reviews the consumption patterns and historical use of Allium vegetables like onions and garlic for their potential antimicrobial and cardiovascular benefits, but reports no new clinical findings.
3 citations
,
January 2005 in “Biological & Pharmaceutical Bulletin” This study reports that the peptide GPIGS, found in Bacillus sp. M18 conditioned medium, may promote hair growth through the PI-3K/Akt pathway and accelerate hair regrowth in mice.
2 citations
,
May 2021 in “Clinical Pharmacology in Drug Development” This phase 1 study reported that after administering supratherapeutic doses of cortexolone 17α‐propionate, a topical antiandrogen intended for hair loss treatment, there was no effect on the QTc interval, indicating no measurable cardiac safety concerns in the concentration range tested.
2 citations
,
March 2019 in “European Journal of Dermatology” This study concluded that shampoos sold in pharmacies generally contain fewer regulated allergens under EU law compared to those sold in mass-market stores or by mail order, and pharmacy-sold baby shampoos were allergen-free.
2 citations
,
September 1974 in “Academy of Management Journal” Karl E. Weick recommended focusing on everyday events and smaller organizations to improve organizational theory.
1 citations
,
December 2022 in “Türk tarım - gıda bilim ve teknoloji dergisi” This review discusses the diversification of tea products and their associated health benefits, highlighting the economic challenges faced by tea-producing countries and the global marketing strategies of the tea industry, but reports no new experimental findings.
1 citations
,
November 2011 in “Dermatologica Sinica” This study found a significant decline in serum zinc levels among women of African descent using hair relaxers and experiencing alopecia, with age at first exposure potentially influencing alopecia development.
1 citations
,
September 2003 in “Journal of the Royal Society of Medicine” The book is a detailed guide on hair and scalp diseases, useful for dermatopathologists.
May 2026 in “Research Square” This research reports that the polyG fragment within the Hoxc13 protein alters its gene regulatory functions, which could have influenced mammalian hair evolution by affecting pathways related to hair follicle development.
April 2026 in “Nowotwory Journal of Oncology” This review provides a clinical guide for safely using dermo-aesthetic treatments to improve the quality of life for oncology patients dealing with treatment-related side effects, emphasizing the importance of consulting with an oncologist before undergoing such procedures.
This study found that 49% of female breast cancer patients treated with CDK4/6 inhibitors for at least three months developed alopecia, which significantly impacted their quality of life, with greater alopecia severity leading to worse emotional and functional well-being.
March 2025 in “Texas Journal of Medical Science” This source reviews factors like gender, hygiene, and psychological stress impacting the prevalence and pattern of skin diseases among youth in India, noting the significant emotional burden these conditions can carry.