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The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Drugmakers are optimistic about targeting the Wnt pathway for new treatments despite past challenges.

Wnt5a may contribute to psoriasis by reducing skin cell growth, blocking skin cell maturation, and increasing inflammation.

Effective PCOS treatments require targeting specific signaling pathways.

Alpinetin helps grow hair by turning on hair stem cells and is safe for use.

Eyelid cells share signaling components but differ in pathway activity.

Finasteride, a hair loss drug, is linked to increased suicidal thoughts, particularly when used for hair loss.

Finasteride use for hair loss is linked to an increased risk of suicidal thoughts and a higher risk of suicide.

Finasteride use is strongly linked to sexual dysfunction, especially in young men treating hair loss.

The conclusion is that finasteride is linked to an increased risk of suicidal thoughts and a higher risk of completed suicide when used for hair loss.

Finasteride alone increases suicide risk, but combining it with other treatments reduces this risk.

Finasteride use linked to increased suicidality in patients under 45.

HPV vaccines are generally safe but need further investigation for rare side effects.

Biologics for severe asthma have known side effects, but some new risks need more study.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Low testosterone can cause a heart rhythm problem in men, but fixing it can prevent the issue.