41 citations
,
July 2012 in “Stem Cells and Development” This study found that low-dose UVB radiation enhances the survival, migration, and hair growth-promoting capacity of adipose-derived stem cells in mice through the generation of reactive oxygen species.
41 citations
,
October 2008 in “The American journal of pathology” This study found that reducing BMP signaling in mouse nipple epithelia, achieved through Noggin overexpression, can convert them into hairy skin with pilosebaceous units.
41 citations
,
July 2002 in “Clinical and Experimental Dermatology” This review evaluates hair growth measurement methods for human scalp hair, suggesting that combining highly resolutive analytical approaches with global calibrated methods is recommended for assessing hair changes in clinical settings.
41 citations
,
December 2019 in “Stem Cell Reviews and Reports” This review discusses the progress in tooth regeneration research and highlights the potential of spatial-temporal release of developmental factors, but it reports no new clinical findings.
40 citations
,
June 2013 in “Biomaterials” This study developed a 3D engineered hair follicle model that mimics the native hair bulb and may aid in drug screening for hair growth therapies.
40 citations
,
July 2017 in “Frontiers in Medicine” This review highlights that in children, hair loss can be attributed to diverse conditions like alopecia areata and tinea capitis, and stresses the importance of a holistic approach to diagnosis and management, including psychosocial support due to limited effective treatments.
35 citations
,
January 2014 in “Journal of Tissue Engineering” This review discusses recent advances in the role of dermal papilla cells and adipocyte lineage cells in hair regeneration, but it reports no new clinical results.
33 citations
,
September 2012 in “Australasian Journal of Dermatology” This article reviews trichoscopic signs of chemotherapy-induced alopecia, including exclamation marks, but reports no new clinical results.
33 citations
,
April 2005 in “British Journal of Dermatology” This study found that age and follicular miniaturization were extremely weak predictors of total hair count in women with hair loss.
32 citations
,
February 2008 in “Developmental dynamics” This study indicates that the Sp6 gene is crucial for the development of skin, teeth, limbs, and lungs in mice, possibly through regulating apoptosis.
31 citations
,
September 2012 in “Human Brain Mapping” In this study, patients with seasonal affective disorder were found to have increased functional connectivity in certain brain networks and higher low-frequency fluctuations compared to healthy controls, which aligns with their attentional and psychomotor symptoms.
29 citations
,
May 2010 in “Ophthalmology” Bimatoprost gel makes eyelashes grow longer, but may cause side effects and should be monitored by an eye doctor.
28 citations
,
March 2010 in “Histochemistry and cell biology” Skin cells can help create early hair-like structures in lab cultures.
28 citations
,
October 2004 in “Differentiation” This study identified a large deletion in the desmoglein 4 gene as the genetic basis of the Iffa Credo "hairless" rat's skin phenotype, linking it to lanceolate hair mutations.
28 citations
,
March 2010 in “Histochemistry and Cell Biology” This study identified specific markers that can distinguish between stem cells in different regions of human scalp hair follicles, offering potential strategies for cell sorting and purification based on these markers.
27 citations
,
September 1999 in “Journal of Investigative Dermatology” This study found that protease nexin-1 mRNA is expressed in human dermal papilla cells and is downregulated by dihydrotestosterone in balding scalp, suggesting a role in male-pattern baldness progression.
24 citations
,
January 2011 in “International Journal of Trichology” This review highlights the light microscopic features of various infectious and non-infectious hair conditions and reports no new clinical results.
24 citations
,
April 2007 in “European Journal of Pharmaceutics and Biopharmaceutics” This study found that artocarpin delivered via alginate/chitosan microparticles effectively suppressed the growth of hamster flank organs compared to artocarpin in solution form, without significant systemic effects.
24 citations
,
February 2006 in “Chinese Medical Journal” This study found that dermal papilla cells cultured in vitro can promote hair follicle regeneration and maintain hair growth, with stronger ET-1 and SCF expression enhancing this regenerative ability.
22 citations
,
June 2002 in “Seminars in cutaneous medicine and surgery” This review discusses the use of laser and flashlamp technology for unwanted hair removal and reports no new clinical results, highlighting challenges with light-colored hair and treatment safety for darker skin tones.
22 citations
,
June 1980 in “International Journal of Dermatology” The document concludes that correct diagnosis of alopecia types is crucial, scalp biopsies are important, and more research is needed.
21 citations
,
January 2017 in “Skin Pharmacology and Physiology” In this noninferiority study, researchers found that a 0.2% caffeine-based topical liquid was not less effective than 5% minoxidil solution in improving hair growth in men with androgenetic alopecia over six months.
21 citations
,
January 2005 in “Skinmed” This article reviews the structural similarities and common disorders of hair and nails, highlighting their joint involvement in congenital and acquired conditions, but it reports no new clinical results.
21 citations
,
April 1982 in “Genetics Research” In this study, researchers observed that mice with the naked gene showed frequent absence of hair cuticle and cortical cells during follicle growth, with abnormal keratin deposition also noted.
20 citations
,
April 1999 in “British journal of plastic surgery” This study found that using a ruby laser for hair removal resulted in a significant average reduction of 56.4% in hair density among participants dissatisfied with other methods.
19 citations
,
July 2015 in “Journal of Ginseng Research” In this study, Korean Red Ginseng showed protective effects against chemotherapy-induced premature hair follicle aging in an in vitro model by modulating specific cellular protein expressions.
19 citations
,
December 2006 in “Archives of dermatology” This notice provides information about JAMA Dermatology's website usage policy, and no research findings are reported.
15 citations
,
July 1999 in “Dermatologic Clinics” This article discusses the potential for targeted therapies in hair loss by exploring inflammatory and cytokine-mediated processes, but it presents no new clinical results.
14 citations
,
March 1995 in “Journal of cell science” This study found that targeting SV40 T antigen expression to hair follicles in transgenic mice caused abnormal hair structure and hair loss, but did not lead to cell immortalization or tumor formation in follicles.
14 citations
,
July 2016 in “Anatomical Science International” This study revealed that in androgenic alopecia, the proximal attachment of the arrector pili muscle to the hair follicle is often lost or significantly reduced.