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Testosterone, DHT, and estradiol significantly affect hair cell growth.

RCS-01 is safe and may help rejuvenate aging skin.

This study observed that interferon β secreted by dermal papilla cells may negatively regulate the growth of outer root sheath cells in hair follicles.

This study found that insulin-like growth factor-I and hepatocyte growth factor increased the chemotactic migration of human hair outer root sheath cells, suggesting these factors have both growth stimulatory and chemotactic effects.

This study suggests that the structure and function of the inner root sheath in mammalian hair may have evolved from simpler forms seen in monotremes, aiding in hair exit without damaging the epidermis.

This study found that CD90+ stem cells with fibroblast-like morphology are present in the lower part of the anagen hair follicle in dogs.

This review discusses insights into the role of lipase H in controlling hair form and texture, emphasizing genetic mutations linked to autosomal recessive woolly hair/hypotrichosis, and reports no new experimental results.

This study observed that activating the Wnt/β-catenin pathway enhances hair follicle stem cell proliferation and differentiation, promoting hair growth and wound healing, and demonstrated the potential for outer root sheath transplants to aid skin repair, although challenges remain for clinical application.

This study describes a new tissue culture method that successfully induces outer root sheath cells from hair follicles to differentiate into a multilayered epithelium with characteristics similar to normal interfollicular epidermis.

This study adapted a method for culturing melanocytes from human hair follicles to horses, successfully creating partially melanotic equine melanocytes, potentially advancing hair follicle biology research across species.

This study found that mesenchymal stem cells sourced from hair follicle outer root sheath showed higher differentiation efficiency and angiogenic potential for vascular graft applications compared to adipose-derived stem cells.

The hair follicle's connective tissue is a key source of a certain collagen in human scalp skin.

This study found that keloid tissues exhibit epithelial-mesenchymal transition-related changes and alterations in gene expression, implicating these processes in the pathogenesis of keloids.

This study reports that EGF at specific concentrations promotes the proliferation and migration of hair follicle ORS cells by activating the Wnt/β-catenin signaling pathway in vitro.

This study found that human hematopoietic mesenchymal stem cells increased the viability and migration of human outer root sheath cells in an in vitro alopecia areata model, involving Wnt/β-catenin and JAK/STAT pathways.

In this study, researchers demonstrated that human hair follicle outer root sheath cells release ATP, serotonin, and histamine in response to mechanical stimulation, which subsequently activates surrounding sensory neurons.

This study demonstrated that autologous mesenchymal stem cells from hair follicles, when combined with a novel gelatin-based hydrogel, showed promising osteogenic potential and could offer a non-invasive alternative for bone regeneration.

MPZL3 protein affects hair growth cycles and could help manage hair loss.

This study found that androgen metabolism within hair follicles varies significantly between compartments, with dermal papillae showing high 5α-reductase activity, suggesting a key role in androgen-driven hair growth responses.

This study found that human hair follicle dermal cells, specifically dermal sheath cells, can serve as an alternative and potentially superior cell source for constructing the dermal component of bioengineered skin in both in vitro and in vivo settings.

Androgen receptors found in monkey scalps, similar to humans, affect hair growth.

In this study, the PLP2 gene was found to promote secondary hair follicle development in Liaoning cashmere goats, with its expression negatively regulated by melatonin and potentially affecting follicle development via the BMP pathway.

This article discusses the structures surrounding hair follicles and introduces aspects like follicle groups and the dermal sheath, but it reports no new research findings.

This study found that dermal sheath stem cell characteristics are lost with aging in humans, affecting skin rejuvenation and structure, and identified specific proteins like Activin A influencing keratinocyte and fibroblast activity.

The researchers reported that DHT-inducible DKK-1 may play a significant role in DHT-driven balding by inhibiting hair follicle cell growth and promoting apoptosis in androgenetic alopecia.

This study identified a new type II cytokeratin, named K6hf, exclusively expressed in the companion layer of the human hair follicle, distinguishing it from other keratins and suggesting a unique biochemical role.

This study found that estrogen receptor beta, not alpha, is the main mediator of estrogen action in human skin and hair follicles, suggesting a distinct role in these tissues.

In this study, researchers found that p75 neurotrophin receptor signaling affects apoptosis during hair follicle regression in mice, and altering its activity might help manage disorders involving early catagen entry.