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This study found that dermal papilla cells in culture may enhance and attract follicular epithelial cell growth, suggesting their pivotal role in hair and follicle development.

This review discusses methods for evaluating hair growth-promoting effects of candidate substances for androgenetic alopecia, focusing on cell assays, organ cultures, and animal models, and reports no new results.

This study observed that testosterone metabolism and androgen receptor localization differ significantly across body sites, with beard hair follicles showing distinct characteristics compared to occipital scalp hair follicles.

This study found that keratoacanthoma of the lip likely arises from outer root sheath cells, based on the presence of specific keratin markers and periodic acid-Schiff staining patterns.

In this study, EGCG from green tea promoted mink hair follicle growth and cell proliferation at specific concentrations, potentially through activation of Shh and AKT signaling pathways.

This study found that experimentally induced calcification in rat skin led to rapid and localized mineralization in hair follicles, progressing to more extensive calcification with prior hypercalcemic treatment.

In this study, EREG promoted hair growth by activating specific receptors in cell and animal models, indicating it may be a potential treatment for hair loss.

This study found that a mutant form of the FGF5s protein, FGF5sC93S, significantly increased hair count after 24 weeks of application on human scalps, suggesting its potential as a hair growth treatment.

This study found that the trichogenicity of cultured human outer root sheath follicular keratinocytes decreased with longer cultivation periods and was significantly influenced by the expression of the transcription factor FOXA2.

This study demonstrated the potential of epithelial cell scaffolds fabricated with various materials for effective hair regeneration, highlighting their promising application in tissue engineering for alopecia treatment.

In this study, Satura® Rosta remedy was found to significantly increase hair follicle size, hair root volume, and skin thickness in mice, potentially by prolonging the anagen phase, with notable hair regrowth observed in older mice with alopecia.

This study suggests that proteins CHI3L1 and CXCL5, secreted by recovery-state dermal papilla cells, may promote hair growth by stimulating the proliferation of outer root sheath cells.

This study suggests that APC collagen peptides may accelerate hair growth and promote overall hair health by enhancing cellular proliferation and activating specific signaling pathways in human and mouse models.

In this study, researchers developed a novel platform for discovering potential hair loss inhibitors by investigating the testosterone/dihydrotestosterone biosynthetic pathway and its regulation through biochemical mechanisms involving 17β-HSD and 3β-HSD, combined with medicinal plant extracts.

This study found that GPR40 agonists may promote hair growth by inducing angiogenesis via specific molecular pathways in both cell and animal models, suggesting potential for hair loss treatment.

In a mouse model, this study found that intradermal keratin injection stimulated hair growth and suggested its potential use for treating hair loss by promoting hair regeneration.

This study found that shikimic acid significantly promoted hair growth in a mouse model and enhanced hair shaft elongation in human hair organ culture, suggesting its potential as a treatment for alopecia.

This study observed that a 3D culture model of hair follicle cells showed an anagen-like phase between days 3 to 6 and transitioned to a catagen-like phase by day 7, highlighting cell differentiation and structural development over time.

This pilot study suggests that autophagy is crucial for anagen maintenance in human hair follicles, and targeting this process may help manage hair growth disorders.

A new method was developed to create better skin models for healing and reconstruction.

This study suggests that minoxidil sulfate and pinacidil do not activate K channel currents in hair follicles, indicating their hair growth effects may occur through other mechanisms like increased blood flow.

This study found that mutations in the hairless gene in mice disrupt hair follicle integrity during catagen, leading to baldness due to disintegrating epithelial structures and loss of normal dermal papilla.

Vitamin D3 affects cell differentiation in specific skin areas.

This study suggests that the MLKL-targeting inhibitor Necrosulfonamide promotes hair growth and counteracts DHT inhibition by activating Wnt signaling in hair follicle cells, revealing potential avenues for anti-alopecia drug development.

This study found that matrix cells from normal hair follicles primarily had a 2C DNA content, while those in androgenetic alopecia showed a significant increase in cells with a higher DNA content.

This study found that LEF1/TCF3 is necessary but not sufficient for TOPGAL activation in hair follicle development, indicating complex regulation in the skin.

In this study, researchers observed that trichocytic and epithelial cytokeratins have distinct expression patterns within various human and bovine hair follicle cells, contributing to understanding hair follicle development and growth.

This study found that estrogen receptor beta, not alpha, is the main mediator of estrogen action in human skin and hair follicles, suggesting a distinct role in these tissues.

This study found that C8/144B antibody exclusively binds to the hair follicle bulge and not the epidermal stratum basale, with cytokeratin 19 serving as a key marker of certain basal keratinocytes that decrease with age.

This study observed that vitamin D receptor expression in certain hair follicle cells varies throughout the murine hair cycle, suggesting a potential role for 1,25-dihydroxyvitamin D3 in hair follicle biology.