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The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Polymeric nanoparticles show promise for treating skin diseases.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Ectodin integrates BMP, SHH, and FGF signals in developing ectodermal organs.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

The Rotterdam Study aims to understand various diseases in older adults.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Laser hair removal is the most requested cosmetic procedure and has become a scientifically-based treatment suitable for all skin types.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Women look young for their age due to larger lips, less sun damage, and genes that prevent gray hair and wrinkles.

Some medicinal plants can help heal wounds and may lead to new treatments.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Latanoprost can make eyelashes longer, thicker, and darker.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.