December 2025 in “Mycoses” In this study involving a murine skin infection model, researchers found that the Trichophyton mentagrophytes strain TIMM 2789, specific to rodents, induced typical symptoms of superficial dermatophytosis, while revealing that the fungal gene SUB6 is not essential for virulence.
September 2024 in “Frontiers in Veterinary Science” In this study, researchers observed that introducing an Environmental Enrichment Program improved the reproductive and zootechnical performance of Calomys callosus rodents by enhancing reproductive indices, parental care, and overall health, including reduced non-infectious lumbar alopecia.
July 2023 in “International Journal of Endocrinology” In this study, researchers observed that Centratherum anthelminticum seed extract effectively reduced cholesterol, triglycerides, insulin resistance, and inflammatory markers, while normalizing hormone levels and oxidative stress markers in rodents with PCOS, suggesting potential benefits for managing the condition.
March 2018 in “Digital Access to Scholarship at Harvard (DASH) (Harvard University)” In this study, chronic stress signals were found to delay hair follicle stem cell activation and negatively impact their niche components in rodents.
October 2013 in “Journal of Investigative Dermatology” Collagen VII helps skin heal and stay strong, sirolimus may lower skin cancer risk in kidney transplant patients, high-molecular-mass hyaluronan helps naked mole rats resist cancer, dermal γδ T cells aid in hair growth in rodents, and overexpression of IL-33 in mouse skin causes itchiness, offering a model for studying allergic inflammation treatments.
3 citations
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September 2021 in “Annals of Plastic Surgery” In this preliminary study, topical treatment with oxygen-carrying micro/nanobubbles hastened the healing of full-thickness burn wounds in a rodent model, compared to saline-treated controls.
May 2021 in “Histochemistry and Cell Biology” This article highlights studies on cholesterol transporter proteins in hair cycles, epithelial-to-mesenchymal transition in cancer, ovarian hormone effects on cell polarity before implantation, and UV effects on rodent skin, without providing new clinical results.
July 2020 in “Stem Cells Translational Medicine” In this study, Caplan et al. found that treatment with human Tregs expanded from umbilical cord blood may modulate immune responses and improve outcomes in a rodent model of traumatic brain injury.
February 2020 in “Bulletin of Experimental Biology and Medicine” Finasteride and GIZh-72 reduce inflammation, with GIZh-72 being more effective.
December 2025 in “Nature Communications” This study in male rats identified a unique type of mechanoreceptor, the club-like ending, which responds only to touch and not to self-motion during whisking, contrasting with other receptors that show mixed selectivity.
44 citations
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May 2012 in “Endocrinology” This review discusses the etiology of polycystic ovary syndrome, emphasizing the role of genetic and environmental factors, and reports no new experimental findings.
43 citations
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January 2006 in “PubMed” This article summarizes findings on the role of androgens and estrogens in male reproductive tissues across species, highlighting the roles of hormone metabolism, receptor distribution, and stress-induced changes.
January 2017 in “Zurich Open Repository and Archive (University of Zurich)” This study presents a new, effective method for delivering dental epithelial stem cells to the jaw, aiming to advance therapies for enamel defects and regeneration.
349 citations
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January 2005 in “The FASEB journal” This review discusses the cutaneous serotoninergic/melatoninergic system's potential role in skin function and resilience against environmental and internal stresses, but does not report new experimental findings.
219 citations
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January 2006 in “Drug Metabolism Reviews” This review discusses how dehydroepiandrosterone (DHEA) may exert its biological effects through multiple receptors and reports no new clinical results.
119 citations
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August 2008 in “BMC Evolutionary Biology” This study found that while the KRTAP gene family is unique to mammals, humans have a similar number of these hair gene types as other primates despite having less body hair.
77 citations
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March 2021 in “Nature” In this study, increased corticosterone from chronic stress prolonged hair follicle stem cell quiescence in mice, inhibiting regeneration, but restoring Gas6 expression overcame this inhibition.
70 citations
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March 2010 in “The Journal of Steroid Biochemistry and Molecular Biology” This study discusses the potential of targeting 11β-HSD1 for treating metabolic syndrome and highlights emerging promising data from human trials on selective 11β-HSD1 inhibitors.
69 citations
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December 2005 in “Nature Clinical Practice Endocrinology & Metabolism” Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.
54 citations
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September 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that vitamin A influences the immune response and hair cycle, affecting the progression of alopecia areata in mouse models.
46 citations
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November 2004 in “Lipids” This study suggests PPAR isotypes play distinct roles in skin, influencing epidermal barrier formation, sebocyte differentiation, and lipid production, with potential implications for treating skin disorders.
36 citations
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March 2002 in “Journal of Biological Chemistry” Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.
35 citations
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May 2008 in “Drug and Alcohol Dependence” Female mice are less affected by certain substances that alter alcohol consumption compared to male mice.
28 citations
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January 2013 in “Journal of Thyroid Research” This review discusses the potential therapeutic use of thyroid hormones on skin conditions, highlighting the need for further research but reporting no new experimental results.
15 citations
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June 2014 in “Behavioural Brain Research” Neurosteroids may help metyrapone reduce cocaine addiction.
3 citations
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July 2018 in “International Journal of Research -GRANTHAALAYAH” This paper compiles previously observed similarities in biomagnetic fields emitted by human hair and mouse vibrissa follicles, with findings supporting distinctive patterns of biomagnetic activity skewed to one side.
2 citations
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April 2017 in “PubMed” This review discusses the connection between hair follicles and dermal adipose tissue, suggesting that improving the adipogenic environment could be important for treating alopecia and enhancing hair restoration procedures, but reports no new results.
1 citations
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January 2024 in “Cellular & Molecular Biology Letters” This review evaluated the potential of adipose-derived stem cells (ADSCs) for burn treatment, finding promising regenerative healing effects, though most findings are at early experimental stages primarily in animal models.
1 citations
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January 2001 in “Journal of Toxicology-cutaneous and Ocular Toxicology” This review discusses the roles of hair follicles and sebaceous glands in percutaneous transport and reports no new results, noting a lack of adequate models and methodologies.
322 citations
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October 2006 in “British Journal of Clinical Pharmacology” This article reviews the history and challenges of warfarin use and suggests that monitoring genetic and environmental factors could improve individualized dosing and safety, but no new results are reported.