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Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Some wound-healing cells can turn into fat cells around new hair growth in mice.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

Alopecia areata, a common autoimmune hair loss condition, often runs in families.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.

Polymeric nanoparticles show promise for treating skin diseases.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The Rotterdam Study aims to understand various diseases in older adults.

5% and 2% minoxidil solutions effectively promote hair growth and reduce hair loss, with 5% being slightly more effective but having more side effects.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.