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RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Men with systemic lupus erythematosus often have more severe symptoms but can respond well to treatment.

Researchers fixed gene mutations causing a skin disease in stem cells, which then improved skin grafts in mice.

Different autoantibody groups in pediatric SLE are linked to specific symptoms and disease outcomes.

MCTD should be considered in children with recurring muscle issues, lupus-like symptoms, and edema.

Garden cress extract may help treat skin inflammation and androgen-related disorders.

Young C57BL/6 mice heal better than BALB/c mice, and older mice heal faster but regenerate worse.

The COVID-19 vaccine is viewed more negatively and causes more side effects than the flu vaccine in Korean patients with lupus.

Tjalma Syndrome is a rare condition in people with lupus, causing fluid buildup and high CA-125 levels, but not due to tumors.

Higher disease activity in systemic lupus erythematosus is strongly linked to more internal organ damage.

Psychosis can be an early sign of neuropsychiatric lupus, treatable with tailored medication.

A woman with undifferentiated connective tissue disease was diagnosed with renal amyloidosis and carpal tunnel syndrome.

Testosterone's muscle-building effects do not require its conversion to DHT.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

A woman with dermatomyositis showed rare skin symptoms, was treated successfully, and her case suggests checking for cancer in similar patients.

Vitamin B12 deficiency can cause skin darkening and increased blood vessels, but treatment can improve symptoms.

The conditions alopecia areata, primary sclerosing cholangitis, and ulcerative colitis may be linked by shared autoimmune and cell death mechanisms.

A woman with a rare type of dermatomyositis improved with low-dose prednisone and methotrexate.

Two patients with lupus had an unusual type of hair loss not typical for the disease but improved with treatment.

RHUPUS should be considered in children with deforming arthritis.

Early identification of lupus through skin signs and blood tests is crucial in India.

Most patients with Cutaneous Lupus Erythematosus are young females, and dermatologists play a key role in diagnosis.

Alopecia is common in lupus patients, causing significant anxiety and is linked to the disease itself.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.