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RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Researchers fixed gene mutations causing a skin disease in stem cells, which then improved skin grafts in mice.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Men with systemic lupus erythematosus often have more severe symptoms but can respond well to treatment.

Different autoantibody groups in pediatric SLE are linked to specific symptoms and disease outcomes.

Garden cress extract may help treat skin inflammation and androgen-related disorders.

MCTD should be considered in children with recurring muscle issues, lupus-like symptoms, and edema.

Young C57BL/6 mice heal better than BALB/c mice, and older mice heal faster but regenerate worse.

The COVID-19 vaccine is viewed more negatively and causes more side effects than the flu vaccine in Korean patients with lupus.

Myositis in lupus patients is linked to skin rash, hair loss, blood issues, and high disease activity.

Higher disease activity in systemic lupus erythematosus is strongly linked to more internal organ damage.

A woman with undifferentiated connective tissue disease was diagnosed with renal amyloidosis and carpal tunnel syndrome.

Psychosis can be an early sign of neuropsychiatric lupus, treatable with tailored medication.

Tjalma Syndrome is a rare condition in people with lupus, causing fluid buildup and high CA-125 levels, but not due to tumors.

Early recognition and management of connective tissue diseases like lupus are crucial in young patients.

Two children with lysinuric protein intolerance showed symptoms similar to lupus.

Pincer nails are rare in lupus patients and may be managed conservatively.

The conditions alopecia areata, primary sclerosing cholangitis, and ulcerative colitis may be linked by shared autoimmune and cell death mechanisms.

Resveratrol-loaded nanoparticles show promise for lung cancer treatment.

Early treatment and regular check-ups are crucial for lupus patients to prevent progression and improve outcomes.

Loss of OGG1 increases skin inflammation and auto-antibodies in lupus.

A woman with dermatomyositis showed rare skin symptoms, was treated successfully, and her case suggests checking for cancer in similar patients.

A woman with a rare type of dermatomyositis improved with low-dose prednisone and methotrexate.

Two patients with lupus had an unusual type of hair loss not typical for the disease but improved with treatment.

Vitamin B12 deficiency can cause skin darkening and increased blood vessels, but treatment can improve symptoms.

Testosterone's muscle-building effects do not require its conversion to DHT.

Most patients with Cutaneous Lupus Erythematosus are young females, and dermatologists play a key role in diagnosis.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Some patients with hair loss after mild COVID-19 had positive tests for certain autoantibodies.

Treatment with methotrexate and prednisolone led to complete hair regrowth and no relapse for 2 years.