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Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Fat cells in the skin help start healing and form important repair cells after injury.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

FFA's causes may include environmental triggers and genetic factors.

Beta-caryophyllene helps improve wound healing in mice, especially in females.

Certain bacteria and fungi are linked to healthy scalps and dandruff, suggesting that the scalp's microbial balance affects its health.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.

Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.

Lymphatic vessels are essential for hair follicle growth and skin regeneration.

Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.

Hoxc genes control hair growth through Wnt signaling.

A blood pressure drug, diltiazem, may also help treat influenza.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.

JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.