research 3D-SeboSkin Model Application in Hidradenitis Suppurativa/Acne Inversa
The 3D-SeboSkin model effectively simulates Hidradenitis suppurativa and is useful for future research.
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research Differential Molecular Signature of Dermal Papilla Cells from Balding and Non-Balding Scalp in 2D, 3D Culture and Co-Culture with Adipose-Derived Stem Cells
Dermal Papilla Cells grown in 3D and with stem cells better mimic natural hair growth conditions than cells grown in 2D.
research Knockout of mTOR/Akt Inhibitor REDD1 Results in Hair Cycle-Independent Dermal Adipose Expansion by Promoting Adipocyte Differentiation
Removing REDD1 in mice increases skin fat by making fat cells larger and more numerous.
research Antifibrogenic Activities of Novel Vitamin D3 Analogs Are Dependent on VDR Expression in Human Fibroblasts
New vitamin D3 forms need the vitamin D receptor to reduce fibrosis in human cells.
research Dipeptidyl-Peptidase 4 (DPP4)-Positive Fibroblasts Are Responsible for Secretion of Pro-Fibrotic Matrix Proteins in Human Skin
DPP4-positive fibroblasts play a major role in producing proteins that lead to skin fibrosis.
research The Wound Healing of Fractional Photothermolysis Mimics Scarless Healing with Minimal Myofibroblast Activation
Fractional photothermolysis helps wounds heal with minimal scarring.
research The ATP-Dependent Chromatin Remodeler BRG1 Controls Epidermal Keratinocyte Migration During Human Cutaneous Wound Healing
BRG1 is essential for skin cells to move and heal wounds properly.
research A Direct Link Between Prss53, Hair Curvature, and Skeletal Dysplasia
The gene Prss53 affects hair shape and bone development in rabbits.
research Catalytic-Dependent and -Independent Activities of Polycomb Repressive Complex 1 Differentially Regulate Skin Stem Cell Specification
PRC1 influences skin stem cell development by both turning genes on and off, affecting hair growth and skin cell types.
research Conditional Ablation of JAK-STAT5 Signaling Induces Anagen Hair Growth
Blocking JAK-STAT5 signaling in mice leads to hair growth.
research Understanding Cellular and Molecular Responses in the Treatment of Pediatric Lymphatic Anomalies
Sirolimus and propranolol may reduce abnormal cell growth and improve lymphatic malformations in children.
research Cutaneous Overexpression of Cyclooxygenase-2 Models Androgenetic Alopecia in Adult Mice
Cyclooxygenase-2 overexpression in mice skin causes hair loss like human androgenetic alopecia.
research Variability in Secretion of Growth Factors by Platelets Is Intrinsic to Alopecia Patients Undergoing Platelet-Rich Plasma Therapy
Hair growth treatment results vary because each patient's platelets release different levels of growth factors.
research Low-Level Laser Therapy for the Treatment of Male and Female-Pattern Hair Loss: A Review of Literature
Low-level laser therapy helps hair growth and reduces hair loss with few side effects.
research Molecular Basis of Hair Follicle Donor Dominance in Androgenetic Alopecia and Sexual Dimorphism of the Skin
Hair loss patterns differ between males and females due to 5 master regulators and JAK-STAT signaling affects hair growth.
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
research Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Different types of skin cells play specific roles in development, healing, and cancer.
research Epigenetic Control of Adult Stem Cell Function
Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
research Molecular Mechanisms of Viral Oncogenesis in Humans
Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.
research The Role of AUTS2 in Neurodevelopment and Human Evolution
The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.
research Sex Differences in SARS-CoV-2 Infection Rates and the Potential Link to Prostate Cancer
Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.
research Identification of Drug-Specific Public TCR Driving Severe Cutaneous Adverse Reactions
Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.
research External Light Activates Hair Follicle Stem Cells Through Eyes Via an ipRGC–SCN–Sympathetic Neural Pathway
Light can turn on hair growth cells through a nerve path starting in the eyes.
research MiR-218-5p Regulates Skin and Hair Follicle Development Through Wnt/β-Catenin Signaling Pathway by Targeting SFRP2
miR-218-5p helps skin and hair growth by targeting SFRP2 and activating a specific signaling pathway.
research The Antiandrogen Enzalutamide Downregulates TMPRSS2 and Reduces Cellular Entry of SARS-CoV-2 in Human Lung Cells
The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.
research Therapeutic Potential of Patient iPSC-Derived Melanocytes in Autologous Transplantation
Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
research A Role of Placental Growth Factor in Hair Growth
Placental growth factor may help treat hair loss.
research Microbiome in the Hair Follicle of Androgenetic Alopecia Patients
Hair loss patients have different microbes in hair follicles, possibly affecting hair loss.
research Transcriptomic Analysis Reveals Critical Genes for the Hair Follicle of Inner Mongolia Cashmere Goat from Catagen to Telogen
Key genes regulate hair follicle phase changes in Inner Mongolia cashmere goats.
research The Genetics of Human Skin Disease
Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.