January 2025 in “Journal of Clinical Medicine” This study found that among Portuguese women with hirsutism, polycystic ovary syndrome was the most prevalent cause, associated with distinct hormonal features and higher BMI compared to controls.
April 2024 in “Cosmetics” Different oils affect hair flexibility and strength, with their impact varying on whether hair is virgin or bleached.
March 2024 in “Nutrients” This study found that individuals with Alopecia Areata had distinct gut microbiome characteristics, including reduced species richness and specific microbial biomarkers, suggesting a potential link with oxidative stress.
January 2024 in “Medicina” This review examines the pathogenesis of androgen excess and dyslipidemia in PCOS and the potential role of statins as a treatment but provides no new clinical results.
April 2026 in “Diagnostics” This study found that skin changes in morbidly obese individuals are associated with underlying metabolic disturbances but are not currently valuable as independent tools for assessing metabolic risk or treatment response.
February 2026 in “Toxicology Letters” This study used an in silico/in vitro approach to identify potential inhibitors of the enzyme SRD5A2, finding that the androgen receptor modulator MK-0773 is a moderate inhibitor, although it does not act as a covalent inhibitor like finasteride.
February 2026 in “Applied Biosciences” In this study, a computational analysis of promoter regions in human fertility-related genes identified several new candidate regulatory motifs, but these require further experimental validation due to the limitations of being an in silico examination.
January 2023 in “Applied sciences” This study suggests that Equisetum debile extracts, particularly the ethyl acetate fraction, may offer natural cosmeceutical benefits for treating hyperpigmentation, delaying skin aging, and remediating hair loss due to androgenic alopecia.
25 citations
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May 2016 in “Progress in Biophysics & Molecular Biology” This article reviews the role of R-spondins and their receptors in bone development and metabolism, highlighting their potential modulatory effects and clinical implications for treating bone loss diseases, but reports no new clinical results.
47 citations
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October 2021 in “Journal of Nanobiotechnology” This study found that hollow polydopamine nanoparticles enhanced the regenerative potency of the peptide RL-QN15, suggesting potential for improved therapeutic approaches in skin wound healing.
17 citations
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October 2006 in “Molecular and Cellular Endocrinology” This study found that the L457(3.43)R mutation in the human luteinizing hormone receptor increases phosphodiesterase activity, reducing hormonal response despite elevated basal cAMP levels.
October 2025 in “Dermatologica Sinica” This study's network meta-analysis reported that botulinum injection combined with red laser and topical minoxidil is most effective for increasing hair density in androgenetic alopecia when using low-level laser therapy.
July 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that back skin mesenchyme from mouse embryos can induce hair follicle formation even before dermal condensate formation, but R-spondin-1 alone or with a Bmp receptor inhibitor was not sufficient for hair follicle induction.
135 citations
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March 2000 in “Journal of Biological Chemistry” This review discusses the roles of the Agouti and Agouti-related proteins in pigmentation and energy regulation and reports no new experimental findings.
49 citations
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January 2004 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This review discusses the development and selectivity of 5 alpha-reductase inhibitors, particularly non-steroidal ones, and reports no new clinical trial results.
1 citations
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January 2024 in “International journal of molecular sciences” This review article addresses how the TRPV4 ion channel helps cells respond to mechanical and environmental stimuli, discussing its role in calcium signaling crucial for tissue repair and fibrosis across various organ systems, and highlighting potential therapeutic targets from animal and disease models.
August 2023 in “Clinical, Cosmetic and Investigational Dermatology” This study identified key trends and influential contributors in skin microbiome research from the past decade, highlighting the growing publication rates, major players like the USA, and prominent researchers such as Gallo RL.
January 2026 in “Bioengineering” In this review, various expression systems for synthesizing recombinant collagen are compared, highlighting their efficiency, modification capabilities, and cost. Key purification techniques are also analyzed, and challenges like reducing R&D costs and improving safety protocols are identified.
1 citations
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November 2021 in “IntechOpen eBooks” This review covers red light Transcranial LED therapy for hippocampal memory impairment in aging and Alzheimer's but reports no clinical results, highlighting a need for further research into its mechanisms and effects.
5 citations
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July 2022 in “Orphanet journal of rare diseases” This study found that RSPO1 mutations in patients with a 46XX disorder of sexual development contribute to impaired skin integrity and increased risk of squamous cell carcinoma in areas subject to friction.
January 2025 in “Dermatological Reviews” This study reports that Cyperus rotundus L. (nut grass) shows promise as a natural hair removal agent, with compounds targeting hair follicles and potentially offering an alternative to chemical depilatories, demonstrated by its efficacy in clinical trials and comparable results to some laser treatments.
August 2025 in “Seminars in Nephrology” Regenerative repair is essential to prevent long-term kidney function issues after obstruction.
8 citations
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July 2024 in “Journal of Advanced Research” In this study, researchers report that CDK inhibitors like palbociclib and ribociclib, initially developed for cancer therapy, show potential in treating neutrophilic inflammation-related conditions such as ARDS and psoriasis, although their clinical repurposing requires further research on safety and dose adjustments.
5 citations
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June 2021 in “chemistry of plant raw material” This review provides information on the biological activity and chemical composition of various Rumex species, finding that some have pharmacological potential, but reports no new experimental results.
May 2025 in “Plastic & Reconstructive Surgery Global Open” In this proof-of-concept study, researchers found that hair grafts preserved in preconditioned autologous platelet-rich plasma with photothermal biostimulation and phosphate-buffered saline remained viable for eight hours before transplantation, outperforming saline solution and Ringer's lactate by two hours.
October 2021 in “VITEK Bidang Kedokteran Hewan” This case study reports on a 1-year-old male goat with various health issues including bloody stool, hair loss, and lice, treated with medication and supplements.
19 citations
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October 1985 in “British Journal of Dermatology” This review proposes a new approach for categorizing and diagnosing unruly hair forms, building on previous literature and clinical experience, without presenting new clinical results.
18 citations
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November 2013 in “Molecules and Cells” This study found that a novel 3D in vitro culture condition improved stemness markers and proliferation potential in human dermal stem/progenitor cells compared to traditional 2D methods.
December 2023 in “International Journal of Molecular Sciences” In this study, researchers found that young men with androgenic alopecia exhibited significantly higher mRNA levels of 5α-reductase isozymes and changes in prostate cancer-related genes, which could explain varying responses to treatment and guide future therapies.
502 citations
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February 2008 in “The Journal of Clinical Endocrinology & Metabolism” This review discusses hirsutism management guidelines, recommending androgen testing only for women with abnormal hirsutism scores and advocating for combined therapy approaches depending on severity and underlying conditions, but it reports no new clinical results.