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The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Mice hair growth patterns get more complex with age and can change with events like pregnancy or injury.

Choosing the right patients, using proper techniques, and having thorough knowledge are key to preventing and managing dermal filler complications.

Oxidative stress contributes to hair graying and loss as we age.

The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.

Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Testosterone's muscle-building effects do not require its conversion to DHT.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Different PIN proteins affect plant root hair growth by changing how auxin is transported.

No single treatment is consistently effective for alopecia areata, and more research is needed.

Many women in southern China have polycystic ovary syndrome, with some symptoms differing from Western women.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

A simple screening method found that 6.3% of women in a semiurban area in Sri Lanka have polycystic ovary syndrome, with most showing menstrual irregularities.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Women with PCOS and higher androgen levels are more likely to have fatty liver disease.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

Alopecia is a key indicator of thallium poisoning.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

Most women with PCOS have high levels of male hormones, and free testosterone is the best marker for this.

Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.