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Severe digestive issues in DRESS need early endoscopy for better treatment.

Case reports are important in medical science for discovering drugs and identifying rare conditions, despite their limitations.

A Japanese bone marrow transplant patient developed a rare skin cancer possibly linked to long-term use of the medication voriconazole.

SLE patients need careful diagnosis to distinguish infections from disease flares for proper treatment.

The link between pemphigus and the patient's scarring hair loss is still unclear.

A woman with systemic sclerosis developed a unique scarring hair loss combining features of systemic sclerosis and frontal fibrosing alopecia.

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

Cancer therapy can cause various skin problems, including hair loss, skin darkening, painful hand-foot syndrome, and severe skin damage.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

Some common medications can harm male fertility, but many effects can be reversed.

Targeted cancer therapies have a significant but lower risk of causing hair loss compared to chemotherapy.

Cyclophosphamide has serious side effects, but long-term follow-up can help manage risks.

People with pemphigus are more likely to have conditions like hypothyroidism, inflammatory bowel disease, and diabetes.

Patients with chronic skin conditions on systemic treatments did not have worse COVID-19 outcomes and could resume their treatments after recovery.

Lower CD200R1 on certain immune cells is linked to more severe rheumatoid arthritis and immune imbalance.

The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.

Hepatitis C virus can cause skin diseases and dermatologists play a crucial role in identifying these conditions.

The European Society of Cutaneous Lupus Erythematosus created a questionnaire to standardize patient assessment and improve care for cutaneous lupus.

The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.

Microneedle technology is beneficial for drug delivery and could make vaccinations cheaper and more accessible.

Methotrexate for rheumatoid arthritis often causes side effects like diarrhea, fatigue, and hair loss, especially at higher doses.

Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.

Oral mTOR inhibitors often cause skin and hair side effects but usually don't require stopping treatment.

Adalimumab helped control a child's severe eye disease when other treatments failed.

A woman's ovarian tumor causing high testosterone was successfully removed, and her symptoms improved.

Hair loss can indicate or worsen with systemic diseases, and treating the underlying condition is important.

Frontal fibrosing alopecia is a scarring hair loss condition mainly affecting older women, with no known cause and treatments that may help stabilize hair loss.

Early diagnosis, intensive therapy, and careful follow-up are crucial for managing overlapping TTP and SLE.