research Generic Competition And Pharmaceutical Patent Strategies: A Sequel
The article concludes that recent legal rulings have strengthened the protection of pharmaceutical patents against generic competition.
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research Nanomilled Oral Testosterone Plus Dutasteride Effectively Normalizes Serum Testosterone in Normal Men With Induced Hypogonadism
A combination of nanomilled oral testosterone and dutasteride normalized testosterone levels in men with low testosterone and is safe for short-term use.
research Testosterone-Secreting Adrenal Adenoma Containing Crystalloids of Reinke in an Adult Female Patient
Leydig cells can cause testosterone-secreting adrenal tumors in women.
research Regulation and Implementation of Pharmaceutical and Other Regulations
Europe strengthened medicine regulations, increased protection against counterfeit drugs, and made it tougher to challenge comparative advertising, while also focusing on patent law enforcement and updating plant protection rules.
research The Investigation and Management of Severe Hyperandrogenism Pre- and Postmenopause: Non-Tumor Disease Is Strongly Associated with Metabolic Syndrome and Typically Responds to Insulin-Sensitization with Metformin
High levels of male hormones in women without tumors are linked to metabolic problems and can be treated with metformin.
research The Chemokine SDF-1/CXCL12 Regulates the Migration of Melanocyte Progenitors in Mouse Hair Follicles
SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
research George Ernest Rogers 1927–2021
George Ernest Rogers was a notable scientist who made important discoveries about hair and wool proteins.
research Iontophoresis of Minoxidil Sulphate Loaded Microparticles: A Strategy for Follicular Drug Targeting?
Iontophoresis improves minoxidil delivery to hair follicles for hair loss treatment.
research Quality of Life in South African Black Women with Alopecia: A Pilot Study
Alopecia greatly lowers the quality of life for South African Black women, especially affecting their self-image and social interactions.
research Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline
The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.
research Words of Wisdom for Newcomers to Hair Restoration Surgery
Newbies to hair restoration surgery should research well, set realistic expectations, and choose experienced surgeons.
research Book Review
The book is highly praised as an essential resource for plastic surgeons, despite minor gaps.
research Use of Platelet-Rich Plasma in the Management of Alopecia Areata
Platelet-Rich Plasma (PRP) may be a safe and effective treatment for hair loss caused by Alopecia Areata.
research The Art of Repair in Surgical Hair Restoration Part I: Basic Repair Strategies
Effective repair of bad hair transplants requires skilled techniques and careful use of donor hair, with strategies like reimplantation and camouflage, and new methods to minimize scarring.
research Dihydrotestosterone and 5α-Reductase: Role in Hair Loss and Prostate Health
Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.
research Evaluation of a Pool of Biomimetic Peptides on Human Hair Follicles: A Preclinical Study
Biomimetic peptides were found to promote hair growth and prolong the growth phase in human hair follicles.
research Alopecia Associated with Fluconazole Therapy
Fluconazole can cause temporary hair loss, which stops after reducing or stopping the drug.
research Effect of Topically Applied Melatonin and Their Combination with Minoxidil Solution for Enhancement of Hair Growth in Male Mice
Melatonin and minoxidil together may improve hair growth when applied to the skin.
research Sparse Haplotype-Based Fine-Scale Local Ancestry Inference at Scale Reveals Recent Selection on Immune Responses
Recent selection on immune response genes was identified across seven ethnicities.
research Rapamycin But Not Acarbose Decreases Age-Related Loss of Outer Hair Cells in the Mouse Cochlea
Rapamycin reduces age-related hearing cell loss in mice, but acarbose does not.
research Genetic Alteration of Cyclic Adenosine 3',5'-Monophosphate-Dependent Protein Kinase Subunit Expression Affects Calcium Currents and Beta-Endorphin Release in AtT-20 Clonal Pituitary Cells
Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.
research Pharmacophore and Atom-Based 3D QSAR Studies on the Novel 5-Alpha-Reductase Inhibitors
The developed model can predict effective 5-alpha-reductase enzyme inhibitors.
research Female Androgenic Alopecia
Women with low SHBG levels and a high 3a-diol G to SHBG ratio are likely to experience female pattern baldness, possibly due to a slight excess of androgens affecting sensitive hair bulbs.
research Medical Treatment of Male Pattern Alopecia (Androgenic Alopecia)
Topical minoxidil is the most promising treatment for male pattern hair loss, but more research is needed to confirm its effectiveness and safety.
research Evidence for Multiple, Developmentally Regulated Isoforms of Ptprq on Hair Cells of the Inner Ear
Ptprq has multiple forms that change during inner ear development.
research Effect of Shampoo, Conditioner, and Permanent Waving on the Molecular Structure of Human Hair
Perming significantly changes hair's molecular structure, while shampoo and conditioner do not.
research Emerging Concepts About Prenatal Genesis, Aberrant Metabolism, and Treatment Paradigms in Polycystic Ovary Syndrome
PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.
research Marked Suppression of Dihydrotestosterone in Men with Benign Prostatic Hyperplasia by Dutasteride, a Dual 5α-Reductase Inhibitor
Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.
research Antagonism of NMDA Receptors as a Potential Treatment for Down Syndrome: A Pilot Randomized Controlled Trial
Memantine may slightly improve memory in people with Down syndrome, but more research is needed.
research Nonsteroidal Inhibitors of Human Type I Steroid 5α-Reductase
New compounds called benzoquinolinones may treat conditions linked to excess DHT.