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April 2017 in “European Urology” Using finasteride for hair loss or prostate issues does not significantly raise the risk of erectile dysfunction.
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May 2024 in “Human Genomics” Among a Han Chinese cohort, this study found that a higher genetic risk score was linked to increased susceptibility to BPH, larger prostate size, reduced effectiveness of 5ARI treatment, and a higher risk of undergoing TURP.
July 2026 in “Journal of the American Academy of Dermatology” GLP-1 and GLP-1/GIP agonists may increase the risk of hair loss.
In this study, long-term low-dose finasteride use in men with alopecia was associated with a significant reduction in the diagnosis of benign prostatic hyperplasia and prostate cancer, although further research is needed to understand the mechanisms and long-term effects.
April 2026 in “The Journal of Sexual Medicine” This study described the population-level incidence of erectile dysfunction in men using finasteride for androgenetic alopecia, finding a varied risk that highlights the complexity of interpreting sexual side effects.
February 2026 in “JAAD International”
September 2025 in “Matics Jurnal Ilmu Komputer dan Teknologi Informasi (Journal of Computer Science and Information Technology)” This study found that among various predictive models for baldness risk, Random Forest Regression performed best with the lowest mean squared error and highest R², indicating strong predictive accuracy, especially with complex datasets, while Linear Regression was better suited to simpler datasets.
August 2025 in “medRxiv (Cold Spring Harbor Laboratory)” This study reports that using 5-alpha reductase inhibitors is associated with a 31% increased risk of depression, highlighting that the choice of comparator group significantly affects study results.
August 2025 in “Journal of the American Academy of Dermatology”
July 2025 in “Dermatology Practical & Conceptual” Spironolactone is safe for treating hair loss in women without causing low blood pressure.
June 2025 in “International Journal of Dermatology”
June 2025 in “JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH” In this observational study, researchers found a strong association between higher alcohol and smoking indices and increased severity of male androgenetic alopecia.
In this study, researchers found that patients with alopecia areata displayed higher systemic inflammatory markers and lower vitamin D levels compared to healthy controls, yet they exhibited similar cardiovascular risk profiles, with no association between inflammation and cardiovascular risk or alopecia severity.
October 2024 in “Skin Appendage Disorders” This study found that lichen planopilaris is associated with several environmental factors, such as stress and hair dye use, as well as thyroid disorders and genetic components.
August 2024 in “Australasian Journal of Dermatology” This study found that finasteride users had a very low rate of psychiatric side effects, with no significant increase in BPH patients and a slight increase in anxiety and depression among AGA patients.
November 2023 in “Journal of Investigative Dermatology” JAK inhibitors are effective and generally safe for treating alopecia areata, but monitoring for side effects is important.
October 2023 in “Journal of the Endocrine Society” In this study, distinct androgen excess subtypes were identified in women with PCOS, with the adrenal androgen excess cluster showing significantly higher rates of insulin resistance and type 2 diabetes, suggesting 11-oxygenated androgens as potential drivers of metabolic risk.
September 2023 in “Research Square (Research Square)” This study describes the development of a prototype clinical expert system that uses a belief rule-based inference methodology to improve the risk stratification and diagnosis of polycystic ovary syndrome by addressing uncertainties in clinical data and domain knowledge.
August 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” In this retrospective study of patients with advanced Merkel cell carcinoma responding to immunotherapy, those treated for 18 months or longer showed better progression-free outcomes compared to shorter treatment durations, indicating potential benefits of extended therapy duration.
June 2023 in “Research Square (Research Square)” This study found that among male Han Chinese, a higher polygenic risk score was linked to increased risk and poorer treatment outcomes for benign prostatic hyperplasia.
May 2022 in “Hormones and behavior” This study found that hair cortisol levels in black-tailed prairie dogs, influenced by factors like predation risk and lactation, were associated with reproductive success, supporting the Cort-Adaptation hypothesis.
May 2022 in “Journal of Education, Health and Sport” This review discusses the associations between dermatological disorders and increased cardiovascular risk, emphasizing that skin conditions with chronic inflammation may elevate the likelihood of cardiovascular diseases.
July 2020 in “Indian journal of sexually transmitted diseases and AIDS” This article highlights the importance of an algorithmic approach to manage multiple opportunistic infections in HIV-infected patients due to the risk of drug interactions and complications, but reports no new clinical results.
February 2020 in “Research Square (Research Square)” In this study, skin tags in Irish adults with morbid obesity were associated with higher blood pressure, higher HbA1c levels, and a greater prevalence of diabetes and hypertension, suggesting increased cardiovascular risk.
April 2019 in “Journal of Investigative Dermatology” This study found that Merkel cell carcinoma recurrence risk peaks within the first two years after diagnosis and varies significantly by stage, with immune suppression, age, and male sex also influencing risk.
April 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study identified a specific genetic variant in the CCHCR1 gene that may contribute to alopecia areata through impaired keratinization, suggesting an alternative mechanism beyond autoimmune causes.
February 2017 in “Cancer Causes & Control” In this study, Swedish men carrying the AR haplotype H2 were found to have a significantly lower risk of prostate cancer compared to those with the more common H1 variant.
April 2007 in “The Journal of Urology” Finasteride reduces bleeding risk during prostate surgery.
March 2020 in “Journal of evolution of medical and dental sciences” In this study, the vertex type of male pattern baldness was associated with increased cardiovascular risk factors, suggesting it may serve as a marker for cardiovascular evaluation in men.
January 2013 in “Faculty of Health; Institute of Health and Biomedical Innovation” This study aimed to identify unknown genetic risk loci associated with androgenetic alopecia by examining SNPs at 12 genomic loci but did not find complete heritable risk factors.