19 citations
,
March 1990 in “Journal of Cardiovascular Pharmacology” Minoxidil affects rat fluid dynamics, altering pressure and circulation, improving blood flow and hair growth.
1 citations
,
February 2022 in “Veterinární Medicína” This report presents the first successful management of minoxidil toxicosis in a cat, detailing the clinical progression and treatment plan used to resolve the condition.
55 citations
,
September 2017 in “Expert Opinion on Drug Discovery” This review examines the main absorption sites and influencing factors for orally administered drugs, highlighting variables such as solubility and gastrointestinal conditions that affect drug absorption in the small intestine and the development of effective drug delivery systems.
153 citations
,
August 2002 in “Dermatologic Surgery” This paper introduces the Follicular Unit Extraction procedure and its accompanying FOX Test, finding that 60% of tested patients were suitable candidates for this minimally invasive hair transplantation method.
13 citations
,
August 2002 in “Dermatologic Surgery” This paper introduces Follicular Unit Extraction and reports the FOX Test can identify suitable candidates, with about 25% of patients being ideal and 35% being good candidates for the procedure.
January 2020 in “Acta Scientiae Veterinariae” In this case report, a combination of ozone therapy, low-level laser, and herbal medicine gel effectively improved healing in a dog with chronic bite wounds.
85 citations
,
March 2002 in “Body & Society” This article reviews the discourse around male cosmetic surgery patients and argues against the perception that cosmetic surgery will become as common among men as it is among women.
33 citations
,
September 1998 in “Dermatologic Surgery” This article proposes a classification for small graft transplants that includes technical factors to improve communication and facilitate comparative studies, reporting no new clinical results.
31 citations
,
October 2017 in “Dermatologic Surgery” This review examines controversies in hair transplant surgery, including donor harvesting techniques and the roles of platelet-rich plasma and low-level light therapy, and reports no new clinical results.
688 citations
,
June 2007 in “Cell Stem Cell” This study found that deleting the ATR gene in adult mice led to rapid onset of age-related traits such as hair graying and osteoporosis through reduced regenerative capacity.
255 citations
,
October 1985 in “The Journal of Clinical Endocrinology & Metabolism” This study concluded that albumin-bound testosterone is biologically important and significantly contributes to testosterone bioavailability in women receiving spironolactone.
119 citations
,
January 2014 in “Indian Journal of Dermatology, Venereology and Leprology” This review discusses the use of platelet-rich plasma in various dermatological applications and reports no new clinical results; the authors call for more rigorous trials to confirm its effectiveness.
82 citations
,
February 1989 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that in men with benign prostatic hyperplasia, a 3-month treatment with a long-acting GnRH agonist significantly reduced intraprostatic DHT and 3α-diol levels by about 90% and testosterone by about 75%.
77 citations
,
February 2017 in “Stem Cell Reports” This study found that activation of Wnt/β-catenin signaling in mouse testes promotes spermatogonial differentiation and reduces the stem cell pool, with SHISA6 inhibiting this process and maintaining stem cell characteristics.
67 citations
,
December 2009 in “Stem Cells” This study found that β-catenin signaling increases in newly born glial cells in the cortex after traumatic brain injury in mice, suggesting potential targets for enhancing recovery through the Wnt/β-catenin pathway.
60 citations
,
November 2009 in “General and Comparative Endocrinology” The researchers reported that during early embryogenesis and larval development in Silurana tropicalis, inhibiting steroidogenic enzymes cyp19 and srd5beta affects genes related to thyroid and reproductive systems.
47 citations
,
November 2002 in “Journal of Neurochemistry” This study found that progesterone pretreatment in rats potentiated the effect of ethanol on mesocortical dopamine levels, suggesting an influence of neuroactive steroids on ethanol's action.
40 citations
,
March 2019 in “Nature Communications” This study found that deleting Stim1 and Stim2 in mature T regulatory cells disrupts Ca 2+ signaling, preventing their differentiation and leading to severe autoimmune disorders in mice.
37 citations
,
January 2009 in “Sexual Development” This study found that chronic exposure to fadrozole or finasteride during frog development induced intersex individuals, which displayed different gene expression profiles depending on the chemical used.
29 citations
,
March 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” This study observed that isoproterenol directs hair-follicle-associated pluripotent stem cells to differentiate into cardiac muscle cells in large numbers, forming tissue sheets of beating heart muscle cells in culture.
26 citations
,
September 1990 in “Ophthalmology” This case study found that a 7-year-old girl's crystalline cataract had sulfur-containing amino acids likely cystine, and was associated with abnormal hair conditions.
19 citations
,
December 2016 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics” This study found that multiple ion channel modulators, used here at clinical concentrations, increased intracellular calcium release in prostate and breast cancer cell lines.
19 citations
,
August 2011 in “Facial Plastic Surgery Clinics of North America” This article discusses the use of hair transplantation as a reconstructive method to restore hair in various areas affected by defects, highlighting its advantages in providing natural-looking restoration.
17 citations
,
June 2015 in “PLOS ONE” This study reported that FDG PET/CT imaging provided additional information that significantly impacted the treatment and prognosis in seven out of ten canine cancer patients, suggesting its potential in veterinary oncology.
15 citations
,
March 2012 in “International journal of nanomedicine” In this study, local injection of nanosized recombinant human erythropoietin at the injury site improved skin regeneration and re-epithelialization in a mouse model of deep second-degree burns through coexpression of specific receptors.
14 citations
,
March 2018 in “Translational Stroke Research” In this animal study, researchers found that finasteride may offer neuroprotective benefits as a post-ischemic treatment for strokes in aged male rats, suggesting its potential as a therapeutic agent in this context.
13 citations
,
September 2018 in “Hair transplant forum international” This article discusses the unique aspects of hair transplantation for achieving natural and dense coverage, but it provides no new clinical results.
13 citations
,
August 2018 in “Facial Plastic Surgery Clinics of North America” This review discusses the potential effectiveness of cell therapy for hair loss, highlighting promising early findings but emphasizing that more research is needed to explore specific therapies like autologous fat grafting and mesenchymal stem cells.
8 citations
,
October 2005 in “Otolaryngologic Clinics of North America” This article discusses the mechanisms and prevention of aging, particularly in facial rejuvenation, but reports no new experimental findings.
8 citations
,
May 1941 in “Science” Inositol helped cure hair loss around rats' eyes and improved their growth.