2 citations
,
July 2022 in “Cell Regeneration” This review discusses the complex interplay of factors controlling hair regeneration and highlights the potential for targeted clinical applications in various hair disorders, while reporting no new clinical results.
2 citations
,
June 2022 in “Phytomedicine” This study found that Shi-Bi-Man, a hair health supplement, significantly promoted hair growth in mice, likely through activation of the FGF signaling pathway.
2 citations
,
April 2022 in “Research Square (Research Square)” This study found that activating PKM2 and Wnt/β-catenin signaling enhanced hair regrowth and hair follicle stem cell proliferation in mice, suggesting a potential alopecia treatment strategy.
2 citations
,
March 2022 in “Applied sciences” In this study, Lespedeza bicolor extract was found to enhance dermal papilla cell proliferation and extend the anagen phase in mice, suggesting its potential as a treatment for alopecia.
2 citations
,
January 2022 in “Experimental Dermatology” This paper proposes that GDNF signaling may enhance skin regeneration and hair follicle formation by influencing dermal fibroblast differentiation, particularly following injury.
2 citations
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March 2021 in “Journal of Cosmetic Dermatology” This study found that human umbilical cord-derived mesenchymal stromal cell-conditioned media was safe and positively affected hair regeneration in 86.6% of participants in a pilot study.
2 citations
,
May 2020 in “Journal of visualized experiments” This study describes a protocol for inducing endogenous reactive oxygen species in mouse skin, which stimulates tissue regeneration and promotes burn healing and hair follicle growth.
2 citations
,
May 2018 in “Journal of Investigative Dermatology” This study found that large excisional wounds in mice can regenerate new hair follicles and fat, whereas similar wounds in rats across seven strains failed to do so, highlighting interspecies differences in regenerative capacity.
2 citations
,
July 2009 in “Medical hypotheses” This article discusses hair transplant techniques and hypothesizes that smaller regenerating units within hair follicles may allow for one-to-many transplantation, potentially increasing hair numbers for those with hair loss, but reports no new experimental results.
2 citations
,
April 2009 in “Bulletin of Experimental Biology and Medicine” Flamena, a liposomal mix, helps skin heal better after a chemical burn.
2 citations
,
January 2006 in “Publicatio UEPG Ciencias Biologicas e da Saude” This review discusses the potential of dental stem cells from deciduous and permanent teeth for tissue regeneration and reports no new experimental results.
1 citations
,
September 2025 in “PLoS ONE” This study observed that in mouse fetuses, reticular contraction by actomyosin is involved in dermal regeneration, and differences in actin and α-SMA localization may determine the switch between regeneration and scar formation, suggesting potential insights for wound regeneration therapy.
1 citations
,
January 2024 in “Theranostics” This source reviews the role of exosomes in regenerative medicine, highlighting their ability to mediate cell communication and transport biomolecules to enhance or impair biological functions, with potential applications in tissue repair and regeneration.
1 citations
,
November 2023 in “Chemical and Biological Technologies in Agriculture” This study found that JUNB enhances hair regeneration in mice by promoting dermal papilla cell proliferation through the Wnt signaling pathway, suggesting JUNB as a potential molecular target for improving cashmere quality and breeding in cashmere goats.
1 citations
,
September 2023 in “eLife” This study found that TLR2 expression in hair follicle stem cells is crucial for hair follicle maintenance and regeneration, with TLR2-dependent activation potentially offering new therapeutic approaches for hair loss prevention through mechanisms involving immune pathways and CEP administration.
1 citations
,
July 2023 in “Chinese Medicine” This study found that Shi-Bi-Man significantly promotes hair regeneration in cynomolgus monkeys by increasing hair follicle stem cells and up-regulating metabolic pathways.
1 citations
,
March 2023 in “Science Translational Medicine” The researchers reported that targeting glycoprotein 130's signaling site in animal models promoted tissue regeneration and reduced osteoarthritis progression through anti-inflammatory and protective effects.
1 citations
,
May 2022 in “Frontiers in medicine” This study found that topical application of metformin significantly enhanced skin regeneration in mechanically stretched skin in rats, likely by boosting the proliferation of skin-derived stem cells.
1 citations
,
January 2022 in “Biocell” This article discusses the potential of mesenchymal stem cell-derived exosomes (MSCs-exosomes) in regenerative medicine, highlighting their beneficial effects like anti-inflammatory and tissue regeneration properties, and noting challenges such as exosome isolation and safety evaluation that need addressing.
1 citations
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January 2022 in “Stem cell biology and regenerative medicine” This review discusses the potential of cell therapies using dermal papilla and dermal sheath cells for androgenetic alopecia, highlighting their ability to reverse hair follicle miniaturization but not yet achieving significant cosmetic efficacy in trials.
1 citations
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November 2021 in “European journal of medical and health sciences” In three patients with diabetic ulcers, this study reported remarkable wound healing and tissue regeneration after 3 to 6 weekly applications of growth factors-rich plasma and membrane treatment.
1 citations
,
May 2021 in “Research Square (Research Square)” This study concluded that controlled micro-injury induces hair regeneration and vitiligo repigmentation in mice, potentially through the Wnt/β-catenin pathway.
1 citations
,
April 2021 in “Journal of Investigative Dermatology” This study found that laboratory and African spiny mice have distinct spatiotemporal patterns in wound-induced hair neogenesis, with the Twist1 pathway playing a central role in epidermal-dermal interactions for hair primordia formation.
1 citations
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April 2020 in “European Journal of Dermatology” This study reported that apremilast treatment did not lead to sustained improvement in SALT scores for most patients with extensive and treatment-resistant alopecia areata.
1 citations
,
February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” This study identified lymphatic vessels as crucial components of the hair follicle stem cell niche, coordinating connections and contributing to hair follicle regeneration in mice.
1 citations
,
January 2019 in “Journal of Nuclear Technologyin Applied Science (JNTAS) (Print)” This study found that low-level laser therapy accelerates skin regeneration in gamma-irradiated mice and enhances the biostimulatory effect on hair follicles.
1 citations
,
January 2019 in “Elsevier eBooks” This chapter reviews the use of electrospun matrices in creating tissue-engineered skin substitutes and reports no new clinical results; it emphasizes the need for a cell-friendly microenvironment.
1 citations
,
August 2016 in “Journal of Investigative Dermatology” This research reported that STAT5 activation in the dermal papilla plays a crucial role in triggering anagen entry during post-developmental hair follicle cycling.
1 citations
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July 2008 in “PubMed” This article reviews the protective and regenerative mechanisms of nerve fibers and Schwann cells after injury but reports no new findings.
This study identified a proliferative intermediate transcriptional state associated with the transition from secondary hair germ cells to lower hair follicle-associated cells during early hair follicle regeneration in mice.