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Skin organoids can regenerate hair by forming specific cell units with certain signals.

This article discusses the potential for rejuvenating self-repair mechanisms to enhance regenerative medicine, but reports no new empirical findings.

In this study, researchers developed a new method called Enriched-GF, which enhances growth factor recovery from platelet concentrates through a combination of glass bead activation, freeze-thaw cycling, and calcium stimulation, outperforming conventional methods by providing higher and more consistent yields for regenerative medicine applications.

This preprint reports meaningful improvements in hair density and scalp coverage in an elderly female with androgenetic alopecia treated through an integrative regenerative protocol, involving microneedling and plant-derived exosomes, among other non-pharmacological interventions focusing on cellular senescence pathways.

In this study, researchers identified wound-induced gene expression programs during regeneration initiation in planarians, highlighting the importance of the runt-1 gene and other conserved genes in the process.

This review discusses recent advancements in regenerative medicine, including functional organ regeneration and the creation of mini-organs, and reports no new clinical results.

In this study, researchers using the hair paradigm highlighted how periodic patterning and compartmentalization enable diverse regenerative behaviors, including region-specific renewal cycles and emergent properties like regenerative waves in organ populations.

This protocol describes a method for regenerating hair follicles using a bioengineering technique called the Organ Germ Method, but it reports no new clinical results.

In a mouse model of deep skin burns, this study found that a neuro-inspired biomimetic microreactor, when delivered through a hydrogel and activated by near-infrared light, significantly promoted functional skin regeneration, sensory recovery, and hair follicle formation.

This study introduces a new multiaxial bioreactor system that uniformly stretches tissue-engineered skin grafts and improves skin tissue maturation through enhanced cellular distribution and environmental monitoring.

The researchers presented a case study on Exo.Reset®, a cosmetic formulation using extracellular vesicle technology, demonstrating systematic application of recognized standards to ensure scientific rigor and regulatory compliance in skin rejuvenation product development, providing a practical model for EV-based cosmetic innovations.

In this study, researchers presented a novel therapeutic approach for androgenetic alopecia combining AR-PROTAC degradation with regenerative strategies and evaluated the potential of GT20029 as a topical treatment, proposing a three-phase protocol and future research hypotheses.

This study found similarities in the regeneration processes of MRL mouse ears and axolotl limbs, involving G2 cell cycle arrest and nerve-dependent mitosis, but the role of p21 in axolotl limb regeneration remains uncertain.

This study introduces Immunoguided Cutaneous Regeneration as a potential framework for understanding skin allotransplantation, suggesting that regeneration may depend on the preserved extracellular matrix and a regulated immune response.

This review discusses epigenetic mechanisms in tissue repair across species and summarizes recent CRISPR-based technologies as promising tools for studying and enhancing tissue regeneration, but reports no new experimental results.

This study suggests that EREG, released from ORS cells, may promote hair growth by activating specific receptors and modulating ROS generation, offering a potential new treatment for hair loss.

This study explores regenerative medicine's potential to improve quality of life, especially in aging populations, by examining key components like triggering agents, potentiators, and additives, and how their combined use may accelerate tissue repair through a strategy called stacking.

This study reports that using a hydrogel-based therapy that dynamically regulates reactive oxygen species helps achieve skin regeneration in infected wounds, promoting organized dermal architecture with improved hair follicle and blood vessel formation, rather than scar formation.

This study developed in vitro methods to regenerate hair follicles and erector muscles by mimicking their native structures and mechanical conditions, reconstructing hair follicle-like structures and forming muscle-like tissues.

This study proposes a new treatment protocol combining autologous regenerative therapy with mesotherapy and photobiostimulation for androgenetic alopecia, leveraging adipose-derived stem cells to stimulate hair follicle regeneration.

This research proposes a comprehensive "four-dimensional technology toolbox" for reprogramming wound-repair cells, aiming to treat chronic non-healing wounds like diabetic foot ulcers by altering fibroblasts, keratinocytes, and macrophages to regenerative phenotypes, and addressing clinical translation challenges.

This paper presents a protocol for differentiating human-induced pluripotent stem cells into keratinocyte progenitor cells and keratinocytes, suggesting potential applications for hair follicle restoration and burn or ulcer therapy.

This study reports that a new artificial skin system using multi-layered hydrogels can promote scarless wound healing and regenerate appendages like hair follicles without cell transplantation.

In this study, researchers achieved complete reepithelialization and hair growth on a burn-injured scalp using a tissue-engineered dermal template with early micrograft hair follicle implantation.

In this study, researchers developed a programmable system using engineered nanovesicles from hair follicle stem cells to modulate immune responses, which showed promise in precisely controlling inflammation, promoting immune balance, and accelerating wound healing, particularly for infected wounds.

This study found that anagen hair follicles can quickly regenerate after radiation damage by forming new progenitor cells outside the bulge, bypassing the need for telogen entry.

This paper describes a protocol for isolating and culturing skin-derived precursors to potentially induce hair growth and regenerate hair follicles, but reports no new experimental findings.

This study review found that stem cells can be transformed into normal skin cells and skin organoids, offering promising methods for regenerating skin integrity and advancing both basic and clinical skin biology research.

Two studies in Cell Stem Cell reported that human and mouse somatic cells can be reprogrammed into induced pluripotent stem cells using microRNAs, eliminating the need for ectopic protein expression.