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Researchers fixed gene mutations causing a skin disease in stem cells, which then improved skin grafts in mice.

The protein called small nuclear ribonucleoprotein polypeptide E is identified as a cause of a type of hair loss without other symptoms.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Early identification of lupus through skin signs and blood tests is crucial in India.

Early treatment of pediatric lupus-related eye issues is crucial to prevent vision loss.

NKG2D gene polymorphism doesn't affect SLE risk but may influence symptoms like rash and hair loss.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Muscles and nerves that cause goosebumps also help control hair growth.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.

Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.

Men with Frontal fibrosing alopecia typically lose hair on the front scalp and sometimes on sideburns and upper lip, with treatments showing varied success.

A woman with subacute cutaneous lupus erythematosus had widespread skin symptoms triggered by medication and sunlight, which improved with specific treatments.

Mice with enhanced regeneration abilities may help develop new regenerative medicine therapies.

Systemic Lupus Erythematosus has varied symptoms and is hard to diagnose, affecting many body parts and requiring careful clinical judgment.

Female donor to male recipient sex mismatch and positive ACA-IgG are key risk factors for vitiligo and alopecia areata in chronic GvHD patients.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.

Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.

Double-stranded RNA causes inflammation in hair follicle cells, which may help understand and treat alopecia areata.

High doses of tryptophan may cause eosinophilic fasciitis.

Non-immune factors play a significant role in alopecia areata.