September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, the reconstructed skin epidermal model derived from hair follicles showed gene expression and enzyme functionality consistent with native human skin, suggesting its viability for studying skin metabolism and potential toxicity of dermo-cosmetic ingredients.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study developed a chitosan-based nanogel for minoxidil, showing in vitro sustained drug release and higher deposition compared to conventional solutions, suggesting potential as an effective topical treatment for alopecia.
January 2025 in “NATIONS UNIVERSITY INTERNATIONAL JOURNAL OF MULTI-DISCIPLINARY STUDIES” This study focused on the formulation of topical gels containing Equisetum arvense extract, evaluating their consistency and preparation using gelling agents for potential application in enhancing drug delivery to wound sites.
1 citations
,
January 2021 in “Arthritis Research & Therapy” The study reported a 7.80% prevalence of scarring alopecia in Chinese SLE patients and identified several risk factors, including mucocutaneous lesions and high disease activity, while renal and cardio-respiratory involvements were negatively associated with it.
16 citations
,
January 2012 in “International Journal of Rheumatology” In this study, weight gain and hair loss were reported as adverse effects of anti-TNF therapy in patients with rheumatic diseases, leading some to discontinue treatment.
4 citations
,
June 2013 in “The Journal of Rheumatology” This abstract describes a program with various presentations and events focused on Canadian excellence in rheumatology but reports no new research findings.
June 2022 in “C&EN global enterprise” This source notes that Olumiant (baricitinib), a rheumatoid arthritis drug by Eli Lilly and Company, has been approved as the first systemic treatment for severe alopecia areata.
June 2016 in “Annals of the Rheumatic Diseases” This study found that glucocorticoid use in rheumatoid arthritis patients is associated with dose-dependent risk of Cushingoid habitus, easy bruising, skin atrophy, and impaired wound healing, while other skin adverse effects are rare at lower doses.
1 citations
,
May 2026 in “Journal of Dermatological Treatment” This case report suggests that starting selective Janus kinase 1 inhibition may improve alopecia in a patient with rheumatoid arthritis who was not responding to TNF-α inhibitor therapy and corticosteroids.
May 2026 in “Indian Dermatology Online Journal” In this case report, a 66-year-old woman with rheumatoid arthritis developed cutaneous ulceration attributed to leflunomide treatment, which significantly healed after discontinuing the drug and administering cholestyramine, underscoring the need for careful monitoring of leflunomide's adverse effects.
November 2016 in “Therapeutic Delivery” New drugs for Alzheimer's and rheumatoid arthritis advanced, a Zika vaccine is in development, and there were business deals in anesthesia and oncology.
122 citations
,
October 2010 in “Clinica Chimica Acta” In this study, washing rhesus monkey hair with water or shampoo significantly reduced cortisol levels, suggesting potential underestimation of chronic stress hormone deposition in hair due to washing.
38 citations
,
January 2017 in “Mediators of Inflammation” This study found that platelet-rich growth factor significantly reduced the release of proinflammatory cytokines in an in vitro rheumatoid arthritis model.
20 citations
,
June 2019 in “JAAD Case Reports” This article reviews the use of tofacitinib for rheumatoid and psoriatic arthritis and alopecia areata, noting potential serious side effects, but reports no cases of palmoplantar pustulosis from the therapy.
16 citations
,
April 2014 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This report describes a case of universal alopecia in a patient with rheumatoid arthritis while using adalimumab and leflunomide, suggesting a potential link between these drugs and alopecia areata.
2 citations
,
January 2024 in “SAGE Open Medical Case Reports” In this case report, a 63-year-old male with rheumatoid arthritis, diabetes, hypertension, and peripheral neuropathy developed drug-induced subacute cutaneous lupus erythematosus after taking Dupilumab for chronic hand dermatitis.
May 2025 in “International Journal of Trichology” In this case report, a 60-year-old man with rheumatoid arthritis and sudden hair whitening was treated with baricitinib, showing significant hair repigmentation and regrowth in 8 months, suggesting potential for baricitinib in managing canities subita, especially when linked to alopecia areata.
January 2024 in “Ankara City Hospital Medical Journal” This case report describes a 42-year-old woman with Rhupus, a rare overlap syndrome of rheumatoid arthritis and systemic lupus erythematosus, highlighting challenges in diagnosis due to non-specific clinical criteria and documenting specific symptoms such as inflammatory arthritis, malar rash, and hematological abnormalities observed during follow-up.
January 2024 in “Ankara City Hospital Medical Journal” This case report details a 42-year-old woman with Rhupus, a rare overlap syndrome of rheumatoid arthritis and systemic lupus erythematosus, emphasizing diagnostic challenges due to non-specific clinical criteria and documenting symptoms like inflammatory arthritis, malar rash, and hematological abnormalities.
November 2023 in “Journal of Pakistan Society of Internal Medicine.” This review discusses the mechanisms, uses, and side effects of conventional synthetic DMARDs, particularly methotrexate, for rheumatoid arthritis, but reports no new clinical findings.
September 2018 in “PubMed” This review discusses various strategies, including vitamin A and dextromethorphan supplementation, to manage methotrexate toxicity and improve adherence in patients with rheumatic diseases, but reports no new clinical results.
26 citations
,
February 2016 in “Respiratory Medicine” This article reviews strategies for serological testing in diagnosing ILD linked to systemic rheumatic diseases and introduces a potential diagnostic algorithm for pulmonologists, while noting further validation is needed.
January 2018 in “Practical diabetes” In this study, leflunomide was effective in treating rheumatoid arthritis, showing comparable efficacy to methotrexate and greater response rates than sulfasalazine, but has significant side effects that require monitoring.
March 2010 in “Anti-inflammatory & anti-allergy agents in medicinal chemistry” This review details the adverse effects and drug interactions of biologic agents used in rheumatoid disease treatment, highlighting their significant side effect profile without reporting new clinical findings.
3 citations
,
August 2020 in “Case Reports in Dermatology” This case report suggests that JAK inhibitors like tofacitinib may effectively treat alopecia in patients with complex cases involving both rheumatological and dermatological conditions.
3 citations
,
June 1983 in “Archives of Dermatology” This article discusses the effectiveness of adrenal cortex compounds E and F in treating connective tissue disorders like rheumatoid arthritis and lupus erythematosus, but it reports no new clinical results.
December 2025 in “Frontiers in Immunology” This review highlights that disturbances in neuroimmune communication, particularly between sympathetic nerves and macrophages, may contribute to autoimmune diseases like rheumatoid arthritis and type 1 diabetes, and suggests potential therapeutic avenues by restoring this communication in preclinical and early clinical studies.
September 2023 in “Nature Biotechnology” This source reports that JAK inhibitors, commonly used in rheumatology, are being explored as new treatment options for autoimmune-driven hair loss, while new understanding of mechanisms is aiding research into androgenic alopecia.
March 2014 in “Human Physiology” This study found that prolonged administration of DHEA improved long-term memory and brain activity balance in old rhesus macaques, with effects like increased motor activity and restored hair lasting a year.
This study suggests that the long non-coding RNA Xist is a key factor in sex differences in systemic lupus erythematosus and rheumatoid arthritis, affecting immune cell behavior and inflammatory pathways in women.