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The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.

Videodermoscopy improves diagnosis of hair and scalp disorders and may reduce scalp biopsies.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

Polymeric nanoparticles show promise for treating skin diseases.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Dermatoscopy is useful for identifying different hair and scalp conditions and can reduce the need for biopsies.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.

Androgens can help prevent memory problems caused by apoE4.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.