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Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Minoxidil and finasteride treat hair loss; more research needed for other options.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.

Oral finasteride works better than topical minoxidil for hair growth, both are safe.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Certain groups may need vitamin supplements to improve hair health and prevent other health problems.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

PRP and HF-MSCs treatment improves hair growth, thickness, and density in androgenetic alopecia.

Nanocapsules can improve clobetasol delivery to hair follicles, reducing side effects.

Bimatoprost is a safe and effective treatment for making eyelashes longer, thicker, and darker.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

Blocking IL-12/IL-23p40 helped reverse severe hair loss in patients.

The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.

Hair loss from hormone therapy in breast cancer patients can be improved with minoxidil treatment.

Some plant-based treatments can help with benign prostatic hyperplasia symptoms, but more research is needed to confirm their safety and effectiveness.

Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.

Baricitinib is effective and safe for treating severe alopecia areata.

Melanocyte development from neural crest cells is complex and influenced by many factors, and better understanding could help treat skin disorders.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

The document concludes that early recognition and treatment of primary cicatricial alopecia is crucial to prevent permanent hair loss.

Mood stabilizers like lithium and anticonvulsants have side effects that can lead to patients stopping their medication, and managing these effects is important for treatment adherence.