2 citations
,
October 2010 in “European Journal of Drug Metabolism and Pharmacokinetics” Researchers developed a quick and sensitive way to measure finasteride in blood using a small sample size.
15 citations
,
November 2006 in “Journal of Pharmaceutical and Biomedical Analysis” This study developed and validated a reliable method to measure finasteride levels in human plasma, which was successfully used to assess its pharmacokinetics after a 5 mg dose in healthy volunteers.
January 2019 in “Arabian Journal of Chemistry” This study developed and validated an HPLC method to quantify impurities in finasteride, demonstrating its suitability for quality assurance of the drug and its related substances.
11 citations
,
April 2013 in “Journal of Proteomics” This study identified proteins that are differentially expressed in balding versus non-balding dermal papilla cells, potentially aiding the understanding and treatment of androgenetic alopecia.
11 citations
,
November 2001 in “Journal of Chromatography B: Biomedical Sciences and Applications” This review discusses various chromatographic methods for analyzing finasteride in biological fluids and provides no clinical findings, focusing on detection techniques for different concentration levels.
7 citations
,
July 2021 in “Molecules/Molecules online/Molecules annual” This study demonstrated that an LC/MS-MS method could effectively detect and quantify the vitamin B3 vitamer nicotinamide in human hair, suggesting its potential use for long-term deficiency examination.
27 citations
,
April 2013 in “Reviews in endocrine and metabolic disorders” The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.
14 citations
,
January 2018 in “Advances in Clinical Chemistry” This review discusses the evaluation of hyperandrogenemia in women and hypogonadism in men across different life stages and presents biomarkers used for diagnosing male hypogonadism, reporting no new clinical results.
467 citations
,
October 2014 in “European Journal of Endocrinology” This paper reviews the diagnostic criteria, etiological factors, and treatment approaches for PCOS, highlighting the importance of considering metabolic issues such as insulin resistance and obesity, but reports no new findings.
157 citations
,
May 2021 in “Endocrine Reviews” This review discusses recent advancements in understanding and managing congenital adrenal hyperplasia, including improvements in screening, diagnostics, and potential genetic and cell-based treatments, but reports no new clinical findings.
January 2023 in “Brazilian Journal of Pharmaceutical Sciences” This study concluded that the liquid chromatography-mass spectrometry method developed is viable for accurately quantifying spironolactone and its metabolite canrenone in plasma despite interference from plasma components.
7 citations
,
November 2022 in “Toxics” This study developed and validated a highly sensitive LC-MS/MS method for detecting multiple steroid hormones in urine and serum/plasma, demonstrating its potential for use in large-scale biomonitoring studies.
January 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that rhamnose can restore hair-inducing gene expression in dermal papilla cells and accelerate hair follicle regeneration by promoting the hair cycle into the anagen phase, suggesting its potential therapeutic application for alopecia treatment.
24 citations
,
July 1994 in “Molecular Endocrinology” Researchers found an RNA transcript that might help control a growth factor linked to tumor development.
39 citations
,
December 2013 in “Phytotherapy Research” This study found that hydroxysafflor yellow A-rich Carthamus tinctorius extract promoted hair growth and gene expression linked to hair proliferation in both cell cultures and mouse models.
3 citations
,
July 2020 in “International Journal of Molecular Sciences” This study reported that molecules from Zebrafish embryo cell differentiation can counteract neurodegeneration, regenerate tissues, and potentially reverse hair follicle damage in androgenetic alopecia.
January 2026 in “Cosmetics” In this study, yeast fermentation of Platycladus orientalis leaves was shown to enhance hair growth-promoting properties by affecting cell cycle phases in human dermal papilla cells, increasing growth factor VEGF, reducing inflammatory factor TGF-β1, and altering the expression of Wnt/β-catenin pathway-related genes.
October 2020 in “Veterinary Dermatology” This review discusses autoimmune blistering diseases across species and highlights new treatment efficacy findings and ongoing trials, but it reports no new clinical results.
44 citations
,
April 2011 in “Critical reviews in analytical chemistry” This review discusses the pharmacological properties and analytical methods for determining fluconazole but reports no new experimental findings.
23 citations
,
January 2017 in “Journal of Oleo Science” This review discusses the use of supercritical carbon dioxide for extracting rice bran oil, noting its advantages over conventional methods for preserving nutrients and antioxidants, but provides no new experimental results.
2 citations
,
November 2023 in “Bioactive materials” The researchers reported that a newly developed ionic liquid-based microemulsion significantly improved the local delivery of copper peptides in mice, enhancing hair growth-related factor activation while offering a safer, non-invasive alternative to existing treatments for hair loss.
In this study, a validated chromatographic method demonstrated the ability to simultaneously analyze gemcitabine and olaparib in pancreatic cancer tissues, supporting the advancement of pharmaceutical formulations combining these drugs, particularly for patients with BRCA mutations.
December 2025 in “Molecules” This study developed a method using UHPLC-MS/MS and MSPE to detect trace amounts of sex hormones in cosmetics, finding progestins and estrogens in some products, and performed a preliminary safety evaluation for residual progesterone in hair loss prevention cosmetics.
August 2025 in “Animal nutrition” This study found that supplementing with 1.5% α-ketoglutaric acid significantly improved the performance, hair follicle density, and antioxidant capacity in Rex rabbits, potentially by enhancing the Wnt signaling pathway and reducing amino acid catabolism.
5 citations
,
February 2013 in “Journal of Liquid Chromatography & Related Technologies” This study developed and validated a micellar electrokinetic chromatography method to determine finasteride stability, finding that the drug degrades under acidic, basic, and oxidative stress conditions.
2 citations
,
March 2022 in “Applied sciences” In this study, Lespedeza bicolor extract was found to enhance dermal papilla cell proliferation and extend the anagen phase in mice, suggesting its potential as a treatment for alopecia.
This study found that while parabens in haircare products were within legal limits, all samples contained dibutyl phthalate, raising concerns about chronic exposure to endocrine disruptors.
December 2025 in “Frontiers in Veterinary Science” This study found that PT-LCG extends hair follicle activity and promotes continuous cashmere growth by enhancing lipid synthesis, remodeling the extracellular matrix, and modulating inflammatory signaling, offering insights into improving cashmere yield and quality through molecular breeding.
136 citations
,
April 2013 in “Clinical Cancer Research” The study found that IPI-926 was well tolerated up to 160 mg once daily for 28-day cycles and showed activity as a single-agent treatment in Hedgehog pathway inhibitor-naïve patients with basal cell carcinoma.
8 citations
,
October 2020 in “Pharmaceutics” This study explored using a chitosan oligomer coating for topical delivery of dutasteride-loaded nanostructured lipid carriers, aiming to reduce systemic exposure and cytotoxicity.